Results 121 to 130 of about 235,984 (237)

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

L-selectin and Cd34 are expressed by human stromal keratocytes

, 2002
Purpose: To identify the expression of CD34 and its' respective ligand L-selectin in human corneal stroma. Methods: 12 human corneas (5 fresh corneas and 7 eye bank corneas) were examined for the expression of CD34 and L-selectin using ...
Joseph, A., Dua, H.S., Hossain, Parwez, Jones, R.   +3 more
core   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Células madre mesenquimales: aspectos relevantes y aplicación clínica en la medicina regenerativa Mesenchymal stem cells: relevant aspects and clinical applications in regenerative medicine

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2013
Se describen los aspectos más relevantes de las células madre mesenquimales que incluyen su plasticidad hacia diversos linajes celulares, como condrocitos, osteocitos y adipositos, entre otros.
Bertha Beatriz Socarrás-Ferrer, Lázaro Orlando del Valle-Pérez, Karelys de la Cuétara-Bernal, Vianed Marsán-Súarez, Miriam Sánchez Segura, Consuelo Macías-Abraham   +5 more
doaj  

Expression of HER2, CD34, and EBV infection in gastric cancer, do they relate?

Journal of Health Sciences
Introduction: Gastric cancer (GC), as a multifactorial disease, exhibits a complex pathogenesis, having intra and inter-tumor heterogeneity, challenging the efficacy of current treatments.
Alexandra Pinheiro, Diana Martins, Clara Rocha, Fernando Melo, Inês Morais, Inês Colaço, Sara Andrade, Rui Caetano, Patrícia Carreira, Fernando Mendes   +9 more
doaj   +1 more source

Extensive phenotypic analysis of CD34 subsets in successive collections of mobilized peripheral blood progenitors

, 1998
The transplantation of mobilized progenitor cells after high-dose chemotherapy shortens haemopoietic engraftment. CD34 cell subsets were examined in 20 consecutive mobilized progenitor cell collections obtained from patients with solid tumours that had ...
Pampallona, S., Leyvraz, S., Gross, N., Peters, R., Perey, L., Schneider, P.   +5 more
core   +1 more source

CD34-positive cells and their subpopulations characterized by flow cytometry analyses on the bone marrow of healthy allogenic donors

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Counting and separating hematopoietic stem cells from different sources has importance for research and clinical assays. Our aims here were to characterize and quantify hematopoietic cell populations in marrow donors and to ...
Jerusa Martins Carvalho, Marlon Knabben de Souza, Valéria Buccheri, Cláudia Viviane Rubens, José Kerbauy, José Salvador Rodrigues de Oliveira   +5 more
doaj   +1 more source

Optimizing cord blood unit selection to improve survival after single‐unit unrelated cord blood transplantation for adult myelodysplastic syndrome

British Journal of Haematology, EarlyView.
Summary Unrelated cord blood transplantation (CBT) is an important alternative donor option for adult patients with myelodysplastic syndrome (MDS); however, the prognostic significance of cord blood unit characteristics following CBT remains unclear and may vary according to disease risk.
Takaaki Konuma, Machiko Fujioka, Kyoko Fuse, Tatsuya Suwabe, Hiroki Hosoi, Naoyuki Uchida, Masatsugu Tanaka, Kazuto Ogura, Satoshi Takahashi, Makoto Onizuka, Takeshi Maeda, Noriko Doki, Yasufumi Uehara, Atsushi Wake, Masatoshi Sakurai, Naoyuki Anzai, Toshimitsu Ueki, Yoshiko Matsuhashi, Koji Kawamura, Fumihiko Ishimaru, Junya Kanda, Marie Ohbiki, Yoshiko Atsuta, Hidehiro Itonaga   +23 more
wiley   +1 more source

Assesment of angiogenesis in basal cell carcinoma using CD31 &CD34 markers and relation with tumor invasiveness in histology [PDF]

Background & Objective : Tumor angiogenesis is essential for tumor growth and appears to play an importating role both in invasive growth and metastasis.
صفايی, زهرا, حديثی, مهدی, فتحي, سولماز, امانی, فیروز   +3 more
core