Results 131 to 140 of about 39,027 (253)

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5476-5491, July 2026.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin, Hui‐Fang Chang, Tzu‐Ching Lin, Cheng‐Han Lin, Yu‐Ling Sun, Chih‐Sheng Lin   +5 more
wiley   +1 more source

A selection model for umbilical cord blood units with high isolation yield of total nucleated and CD34+ cells. [PDF]

Stem Cells Transl Med
Pham VM, Nguyen HV, Dang QT, Nguyen SK, Ngo MHV, Tra APN, Truong HTT, Pham HM, Mai DV, Le OH, Huynh LT.   +10 more
europepmc   +1 more source

Bifunctional Surfaces With Immobilized Antibodies and Bioactive Peptides Mediate Selective Capture and Proliferation of Endothelial Colony‐Forming Cells

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
A tunable bifunctional surface is developed by combining Fc‐binding peptides and RGD motifs to present oriented antibodies alongside integrin‐mediated signaling. The platform selectively captures endothelial colony‐forming cells while promoting their adhesion and proliferation.
Hugo A. Level, Marc‐Antoine Campeau, Mohamed A. Elkhodiry, Gaétan Laroche, Jean‐François Tanguay, Corinne A. Hoesli   +5 more
wiley   +1 more source

Standardized Instance-Level Quantification of CD34-Positive Vessels in Lymph Node Whole-Slide Images Using U-Net. [PDF]

Pathol Int
Omotani S, Yonemoto N, Muramoto A, Kobayashi M.   +3 more
europepmc   +1 more source

Decoding Leukemic Stem Cells in AML: From Identification to Targeted Eradication. [PDF]

Diseases
Apostolidou E, Georgoulis V, Leonardos D, Benetatos L, Kapsali E, Hatzimichael E.   +5 more
europepmc   +1 more source

Loss of CD38 antigen on CD34+CD38+ cells during short-term culture [PDF]

Leukemia, 2000
D, von Laer, A, Corovic, B, Vogt, B, Fehse, S, Roscher, A, Rimek, C, Baum, W, Ostertag   +7 more
openaire   +2 more sources

Bone Marrow Failure Model Mimics Aplastic Anemia Patients: Single‐Cell Landscape of Immune Response Reveals Novel Mechanisms of Immune Imbalance in AA

Cancer Medicine, Volume 15, Issue 6, June 2026.
Single‐cell RNA‐seq is used in a mouse model of immune‐mediated bone marrow failure. Approach to platelets and mitochondrial data. Analysis of various immune cell landscapes, interactions and driving factors in BMF, involving platelets, CD4+ T Cells, CD8+ T Cells, macrophages, and mitochondrial energy metabolism pathways.
Shuai Tan, Fang Fang, Jing Sun, Yumeng Li, Yaochi Chen, Wanling Sun   +5 more
wiley   +1 more source

Endothelial progenitor cell numbers vary in newborns and adults; anti-gm-CSFα (CD116) antibody as a novel marker for EPC enumeration. [PDF]

Innate Immun
Simsek S, Karaca C, Koker N, Öztürk A, Koker MY.   +4 more
europepmc   +1 more source

Prospects of Chimeric Antigen Receptor T-Cell Therapy in Myelofibrosis: From Immunopathogenesis to Therapeutic Strategies. [PDF]

Cancers (Basel)
Kong L, Fu C, Song L, Wang W, Ji M, Li F, Shi X, Chen W.   +7 more
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source