Results 191 to 200 of about 1,140,023 (299)

Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy

HemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT The B‐cell lymphoma 2 (BCL‐2) inhibitor venetoclax (VEN) in combination with hypomethylating agents (HMAs) has improved treatment outcomes for acute myeloid leukemia (AML) patients unfit for intensive chemotherapy and is increasingly used in the relapsed/refractory setting. However, primary resistance remains a significant challenge, affecting
Ida Vänttinen, Joseph Saad, Tanja Ruokoranta, Sari Kytölä, Guangrong Qin, Bahar Tercan, Pia Ettala, Anu Partanen, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mikko Manninen, Peter J. M. Valk, Gerwin Huls, Vésteinn Thorsson, Caroline A. Heckman, Mika Kontro, Heikki Kuusanmäki   +17 more
wiley   +1 more source

CAR-NK cell for gynecological cancers: immune microenvironment remodeling and immunotherapeutic strategies. [PDF]

Front Immunol
Huang M, Wang S, Huang H, Li L, Wang T.
europepmc   +1 more source

Phenotypical characteristics of acute myelocytic leukemia associated with the t(8;21)(q22;q22) chromosomal abnormality: frequent expression of immature B-cell antigen CD19 together with stem cell antigen CD34.

Blood, 1992
K. Kita, K. Nakase, H. Miwa, M. Masuya, K. Nishii, N. Morita, N. Takakura, A. Otsuji, S. Shirakawa, T. Ueda, K. Nasu, T. Kyo, H. Dohy, N. Kamada   +13 more
semanticscholar   +1 more source

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li, Yuezhou Wu, Zhu'anzhen Zheng, Fengjin Zhou, Ke Xu, Jiacan Su   +5 more
wiley   +1 more source

Mixed-phenotype acute leukemia, not otherwise specified, rare types B/T leukemia: a case report in the Jordanian Royal Medical Services. [PDF]

J Med Life
Ogeilat T, Al-Zghoul B, Maaita MJ, Al Zghoul A, Alkishk AA, Alqatamin H, Alnawaflh M, ALfarajat F, Masalha M, Qatawneh M, Al-Dabbas D, Shawabkah H, Al Qudah M, Mohammad A.   +13 more
europepmc   +1 more source

Loss of CD38 antigen on CD34+CD38+ cells during short-term culture [PDF]

Leukemia, 2000
D, von Laer, A, Corovic, B, Vogt, B, Fehse, S, Roscher, A, Rimek, C, Baum, W, Ostertag   +7 more
openaire   +2 more sources

Myelodysplastic/Myeloproliferative Neoplasm in a Dog: A Case Report

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This is a bone marrow aspirate smear image from an 18‐year‐old mixed‐breed dog diagnosed with myelodysplastic/myeloproliferative neoplasm. Both peripheral blood and bone marrow examinations revealed marked myeloid hyperplasia and dysplastic changes. ABSTRACT Myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) is a clonal myeloid disorder ...
Sumin Cha, DoHyeon Yu, Hyeona Bae
wiley   +1 more source

Serum-free differentiation platform for the generation of B lymphocytes and natural killer cells from human CD34+ cord blood progenitors. [PDF]

Sci Rep
Bhave R, Kath CJ, Rüchel N, Vasileiou E, Jepsen VH, Raba K, Pandyra AA, Fischer U, Kogler G.   +8 more
europepmc   +1 more source

Comparison of Diagnostic Utilities in a Canine Retrobulbar Large B‐Cell Lymphoma With Multifocal Involvement

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This case details a rare retrobulbar lymphoma with multifocal involvement. Diagnostic modalities included MRI/CT, cytology of various sites, immunophenotyping and PARR. These tests confirmed diverse cellular populations and Ig clonality across affected tissues. ABSTRACT Lymphoma is the most common malignant neoplasm in dogs.
Rankyung Jung, Hyeona Bae, Kyu‐Woan Cho, Dong‐In Jung, DoHyeon Yu   +4 more
wiley   +1 more source

Evaluation of peripheral blood stem cell collection in the Japan Marrow Donor Program (JMDP). [PDF]

Transfusion
Yamazaki R, Yakushijin K, Yoshihara S, Ikeda K, Ishida A, Kajiwara M, Kikuta A, Takagi N, Nagamura-Inoue T, Namba N, Haraguchi K, Fujimori Y, Fujiwara SI, Yamada-Fujiwara M, Okuyama Y, Tanosaki R, Ueda Y.   +16 more
europepmc   +1 more source