Results 1 to 10 of about 3,143,835 (195)

Impact of Echinococcus granulosus Antigens on Monocyte Development and Dendritic Cell Differentiation [PDF]

Iranian Journal of Immunology, 2023
Background: Different subtypes of dendritic cells (DCs) can induce different types of immune responses. Our previous study found that Echinococcus granulosus (E.
Mingxia Wang, Fei Qiao, Zihua Li, Qiang Wang, Zailing Shang, Junhu Hei, Xuelin Ma, Yana Wang   +7 more
doaj   +1 more source

Focal neuroendocrine differentiation in prostatic gland carcinoma with basaloid pattern [PDF]

Vojnosanitetski Pregled, 2011
Introduction. Prostatic gland basal cell proliferations exhibit morphological continuum ranging from basal cell hyperplasia to basal cell carcinoma.
Gligorijević Jasmina V., Veličković Ljubinka V., Jančić Snežana A., Radovanović Zoran, Krstić Miljan S., Katić Vuka V.   +5 more
doaj   +1 more source

Reactivity of commercially available monoclonal antibodies to human CD antigens with peripheral blood leucocytes of dromedary camels (Camelus dromedarius) [PDF]

Open Veterinary Journal, 2017
Monoclonal antibodies (mAbs) to cell surface molecules have been proven as a key tool for phenotypic and functional characterization of the cellular immune response.
Jamal Hussen, Turke Shawaf, Abdulkareem Imran Al-herz, Hussain R. Alturaifi, Ahmed M. Alluwaimi   +4 more
doaj   +1 more source

Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing

Scientific Reports, 2021
We xeno-transplanted human neural precursor cells derived from induced pluripotent stem cells into the cerebellum and brainstem of mice and rats during prenatal development or the first postnatal week.
Giulia Nato, Alessandro Corti, Elena Parmigiani, Elena Jachetti, Daniele Lecis, Mario Paolo Colombo, Domenico Delia, Annalisa Buffo, Lorenzo Magrassi   +8 more
doaj   +1 more source

Rescuing ESAT-6 Specific CD4 T Cells From Terminal Differentiation Is Critical for Long-Term Control of Murine Mtb Infection

Frontiers in Immunology, 2020
In most cases, Mycobacterium tuberculosis (Mtb) causes life-long chronic infections, which poses unique challenges for the immune system. Most of the current tuberculosis (TB) subunit vaccines incorporate immunodominant antigens and at this point, it is ...
Helena Strand Clemmensen, Helena Strand Clemmensen, Niels Peter Hell Knudsen, Rolf Billeskov, Ida Rosenkrands, Gregers Jungersen, Gregers Jungersen, Claus Aagaard, Peter Andersen, Peter Andersen, Rasmus Mortensen   +10 more
doaj   +1 more source

Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo

Immunity, 2020
How antigen valency affects B cells in vivo during immune responses is not well understood. Here, using HIV immunogens with defined valencies ranging from 1 to 60, we investigated the role of antigen valency during different phases of B cell responses ...
Y. Kato, R. Abbott, B. Freeman, Sonya Haupt, Bettina Groschel, Murillo Silva, Sergey Menis, D. Irvine, W. Schief, S. Crotty   +9 more
semanticscholar   +1 more source

Chronic LCMV infection regulates the effector T cell response by inducing the generation of less immunogenic dendritic cells

Experimental and Molecular Medicine, 2023
Chronic viral infection impairs systemic immunity in the host; however, the mechanism underlying the dysfunction of immune cells in chronic viral infection is incompletely understood. In this study, we studied the lineage differentiation of hematopoietic
Seungbo Yoo, Yun Hee Jeong, Hong-Hee Choi, Sehyun Chae, Daehee Hwang, Sung Jae Shin, Sang-Jun Ha   +6 more
doaj   +1 more source

How Thymocyte Deletion in the Cortex May Curtail Antigen-Specific T-Regulatory Cell Development in the Medulla

Frontiers in Immunology, 2022
CD4+ T cell responses to self-antigens are pivotal for immunological self-tolerance. Activation of Foxp3– T-conventional (T-conv) cells can precipitate autoimmune disease, whereas activation of Foxp3+ T-regulatory (T-reg) cells is essential to prevent ...
Chenglong Wang, Stephen R. Daley
doaj   +1 more source

Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis. [PDF]

PLoS Pathogens, 2009
Even in the absence of an adaptive immune system in murine models, lymphatic dilatation and dysfunction occur in filarial infections, although severe irreversible lymphedema and elephantiasis appears to require an intact adaptive immune response in human
Sasisekhar Bennuru, Thomas B Nutman
doaj   +1 more source

Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells. [PDF]

PLoS ONE, 2014
In an effort to enhance antigen-specific T cell recognition of cancer cells, we have examined numerous modulators of antigen-expression. In this report we demonstrate that twelve different Hsp90 inhibitors (iHsp90) share the ability to increase the ...
Timothy J Haggerty, Ian S Dunn, Lenora B Rose, Estelle E Newton, Franco Pandolfi, James T Kurnick   +5 more
doaj   +1 more source