Results 21 to 30 of about 367,534 (310)
Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production [PDF]
Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts.
Domaschenz, Heather +8 more
core +1 more source
The immune response to malaria in utero. [PDF]
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source
The Oral Tolerance as a Complex Network Phenomenon [PDF]
Date of Acceptance: 23/05/2015 Funding: MSB acknowledges the Engineering and Physical Sciences Research Council (EPSRC) - UK grant EP/I032606/1. PJM and MD received regular scholarships from the Brazilian the following agency: Higher Education Personnel ...
Baptista, Murilo Da Silva +5 more
core +2 more sources
Follicular T helper cells (Tfh) are crucial for effective antibody responses and long term T cell-dependent humoral immunity. Although many studies are devoted to this novel T helper cell population, the molecular mechanisms governing Tfh cell ...
Delphine Debuisson +4 more
doaj +1 more source
The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita +6 more
core +1 more source
Two specific monoclonal antibodies for breast tissue (DF3 and MCAb-12) and the corresponding tumor markers CA15-3 and MCA in serum have been evaluated in 50 patients with breast cancer and in 15 controls.
M.R. Giovagnoli +6 more
doaj +1 more source
Hepatic stellate cells and parasite-induced liver fibrosis
Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Li Yuesheng S +3 more
doaj +1 more source
Failure to account for genetic diversity of antigens during vaccine design may lead to vaccine escape. To evaluate the vaccine escape potential of antigens used in vaccines currently in development or clinical testing, we surveyed the genetic diversity ...
Amed Ouattara +9 more
doaj +1 more source
Definition of Drosophila hemocyte subsets by cell-type specific antigens. [PDF]
We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria.
Andó, István +9 more
core +1 more source
Immune checkpoint inhibitors (ICIs) have improved the survival of patients with non-small cell lung cancer (NSCLC) by reinvigorating tumor-specific T cell responses.
Fiamma Berner +30 more
doaj +1 more source

