Results 21 to 30 of about 367,534 (310)

Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production [PDF]

open access: yes, 2016
Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts.
Domaschenz, Heather   +8 more
core   +1 more source

The immune response to malaria in utero. [PDF]

open access: yes, 2020
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core   +1 more source

The Oral Tolerance as a Complex Network Phenomenon [PDF]

open access: yes, 2015
Date of Acceptance: 23/05/2015 Funding: MSB acknowledges the Engineering and Physical Sciences Research Council (EPSRC) - UK grant EP/I032606/1. PJM and MD received regular scholarships from the Brazilian the following agency: Higher Education Personnel ...
Baptista, Murilo Da Silva   +5 more
core   +2 more sources

Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo.

open access: yesPLoS ONE, 2013
Follicular T helper cells (Tfh) are crucial for effective antibody responses and long term T cell-dependent humoral immunity. Although many studies are devoted to this novel T helper cell population, the molecular mechanisms governing Tfh cell ...
Delphine Debuisson   +4 more
doaj   +1 more source

The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]

open access: yes, 2015
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita   +6 more
core   +1 more source

Evaluation of the Expression of Tissue DF-3 and MCA and the Corresponding Serum Values in Patients with Breast Carcinoma

open access: yesThe International Journal of Biological Markers, 1994
Two specific monoclonal antibodies for breast tissue (DF3 and MCAb-12) and the corresponding tumor markers CA15-3 and MCA in serum have been evaluated in 50 patients with breast cancer and in 15 controls.
M.R. Giovagnoli   +6 more
doaj   +1 more source

Hepatic stellate cells and parasite-induced liver fibrosis

open access: yesParasites & Vectors, 2010
Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Li Yuesheng S   +3 more
doaj   +1 more source

An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes

open access: yesMicroorganisms, 2022
Failure to account for genetic diversity of antigens during vaccine design may lead to vaccine escape. To evaluate the vaccine escape potential of antigens used in vaccines currently in development or clinical testing, we surveyed the genetic diversity ...
Amed Ouattara   +9 more
doaj   +1 more source

Definition of Drosophila hemocyte subsets by cell-type specific antigens. [PDF]

open access: yes, 2007
We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria.
Andó, István   +9 more
core   +1 more source

Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival

open access: yesOncoImmunology, 2021
Immune checkpoint inhibitors (ICIs) have improved the survival of patients with non-small cell lung cancer (NSCLC) by reinvigorating tumor-specific T cell responses.
Fiamma Berner   +30 more
doaj   +1 more source

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