Results 21 to 30 of about 371,078 (308)

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling

Journal of Orthopaedic Surgery and Research, 2023
Background Transglutaminase 2 (TGM2) is a gene previously reported to be associated with the differentiation of bone marrow mesenchymal stem cells (BMSCs). The study was developed to reveal the impact of TGM2 on the migration and differentiation of BMSCs.
Feng Liu, Mingzheng Wu, Xixia Wu, Dan Chen, Ming Xie, Hao Pan   +5 more
doaj   +1 more source

Autoantibody signature differentiates Wilms tumor patients from neuroblastoma patients. [PDF]

PLoS ONE, 2011
Several studies report autoantibody signatures in cancer. The majority of these studies analyzed adult tumors and compared the seroreactivity pattern of tumor patients with the pattern in healthy controls.
Jana Schmitt, Andreas Keller, Nasenien Nourkami-Tutdibi, Sabrina Heisel, Nunja Habel, Petra Leidinger, Nicole Ludwig, Manfred Gessler, Norbert Graf, Frank Berthold, Hans-Peter Lenhof, Eckart Meese   +11 more
doaj   +1 more source

ROC-Analysis of the Results as regards B. pseudomallei and B. mallei Agents Detection Using Solid-Phase ELISA

Проблемы особо опасных инфекций, 2013
Analyzed are operational characteristic curves (ROC-curves) of solid-phase ELISA variants with immune sera to cellular and extracellular Burkholderia antigens with the aim to determine the most effective ones for B. pseudomallei and
A. A. Budchenko, I. Yu. Mazurova, V. I. Ilyukhin, N. P. Khrapova   +3 more
doaj   +1 more source

Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo.

PLoS ONE, 2013
Follicular T helper cells (Tfh) are crucial for effective antibody responses and long term T cell-dependent humoral immunity. Although many studies are devoted to this novel T helper cell population, the molecular mechanisms governing Tfh cell ...
Delphine Debuisson, Nathalie Mari, Sébastien Denanglaire, Oberdan Leo, Fabienne Andris   +4 more
doaj   +1 more source

Evaluation of the Expression of Tissue DF-3 and MCA and the Corresponding Serum Values in Patients with Breast Carcinoma

The International Journal of Biological Markers, 1994
Two specific monoclonal antibodies for breast tissue (DF3 and MCAb-12) and the corresponding tumor markers CA15-3 and MCA in serum have been evaluated in 50 patients with breast cancer and in 15 controls.
M.R. Giovagnoli, G. Reale, L. Cosentino, A. Manna, C. Midulla, G. Marchei, A. Vecchione   +6 more
doaj   +1 more source

Hepatic stellate cells and parasite-induced liver fibrosis

Parasites & Vectors, 2010
Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well ...
Li Yuesheng S, Allen Jeremy T, Anthony Barrie, McManus Donald P   +3 more
doaj   +1 more source

Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production [PDF]

, 2016
Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts.
Domaschenz, Heather, Fung, Herman, Goodnow, Christopher, Horikawa, Keisuke, Jeelall, Yogeshraj, Kallies, Axel, Law, Hsei-Di, Nutt, Stephen L, Wang, James   +8 more
core   +1 more source

An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes

Microorganisms, 2022
Failure to account for genetic diversity of antigens during vaccine design may lead to vaccine escape. To evaluate the vaccine escape potential of antigens used in vaccines currently in development or clinical testing, we surveyed the genetic diversity ...
Amed Ouattara, Ankit Dwivedi, Matthew Adams, Amadou Niangaly, Matthew B. Laurens, Myaing M. Nyunt, Christopher V. Plowe, Abdoulaye Djimde, Shannon Takala-Harrison, Joana C. Silva   +9 more
doaj   +1 more source

Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival

OncoImmunology, 2021
Immune checkpoint inhibitors (ICIs) have improved the survival of patients with non-small cell lung cancer (NSCLC) by reinvigorating tumor-specific T cell responses.
Fiamma Berner, Rebekka Niederer, Jolien J. Luimstra, Oltin Tiberiu Pop, Ann-Kristin Jochum, Mette-Triin Purde, Omar Hasan Ali, David Bomze, Jens Bauer, Lena Katharina Freudenmann, Ana Marcu, Eva-Maria Wolfschmitt, Sebastian Haen, Thorben Gross, Marissa Lisa Dubbelaar, Marie-Therese Abdou, Petra Baumgaertner, Christina Appenzeller, Caroline Cicin-Sain, Tobias Lenz, Daniel E. Speiser, Burkhard Ludewig, Christoph Driessen, Markus Jörger, Martin Früh, Wolfram Jochum, Antonio Cozzio, Hans-Georg Rammensee, Juliane Walz, Jacques Neefjes, Lukas Flatz   +30 more
doaj   +1 more source

Regulated progression of B lymphocyte differentiation from cultured fetal liver. [PDF]

, 1987
Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro.
Denis, KA, Dorshkind, K, Witte, ON
core   +2 more sources