Monoclonal antibodies that detect differentiation surface antigens on human myelomonocytic cells [PDF]
Abstract We describe here the production and characterization of several new monoclonal antibodies that recognize differentiation antigens present on human cells of the myelomonocytic lineage. The lineage and the stage specificities of our reagents (myeloid-, monocytic-, and myelomonocytic- specific) were determined on the basis of their
B, Perussia +5 more
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Differential expression of MHC class II antigens in myelomonocytic leukemia cell lines [PDF]
Major histocompatibility complex (MHC) class II antigens are discordantly expressed on hematopoietic progenitor cells. Their expression is linked to differential responsiveness of the cells to growth factors and inhibitors. We examined the expression of different MHC class II antigens in a panel of human myelomonocytic cell lines representing different
J J, Yunis +3 more
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Relationship between myelomonocytic, myeloid and nonspecific cross-reacting (NCA) antigens during myelocytic cell differentiation [PDF]
La distribution dans les membranes des determinants antigeniques reagissant avec VIM-2 et VIM-D5 dans des leucemies myeloides aigues et chroniques depend des divers stades de la differenciation des granulocytes. Cette etude montre la coexistence de cellules antigene-positives et antigene-negatives dans une population leucemique donnee et aucune dans la
Harłozińska, Antonina +4 more
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Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen [PDF]
Acute myelogenous leukemia (AML) cells express CD23 surface antigen after in vitro treatment with various cytokines, including interleukin- 4 (IL-4) and interferon gamma. Subsequent ligation of CD23 by specific monoclonal antibody (MoAb) induces substantial morphologic and functional modifications in these cells.
F, Ouaaz +9 more
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Terminal differentiation surface antigens of myelomonocytic cells are expressed in human promyelocytic leukemia cells (HL60) treated with chemical inducers [PDF]
The expression of two surface antigens present on the cell membrane of both human granulocytes and monocytes was studied during the process of myelomonocytic differentiation using two monoclonal antibodies (B9.8.1 and B13.4.1). These surface antigens are not present on immature myeloid cells nor on nonmyeloid hematopoietic cells, but can be detected ...
B, Perussia +4 more
openaire +3 more sources
CXCR4 pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis [PDF]
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
CAMPIONI, Diana +8 more
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Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]
Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Burghard F. Klapp +11 more
core +14 more sources
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
core +1 more source
Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers +12 more
core +1 more source
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy [PDF]
Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal antibodies (MAbs) developed for cancer immunotherapy.
Mai, Antonello +3 more
core +1 more source

