Results 11 to 20 of about 5,235 (153)

A novel self-lipid antigen targets human T cells against CD1c(+) leukemias [PDF]

, 2014
T cells that recognize self-lipids presented by CD1c are frequent in the peripheral blood of healthy individuals and kill transformed hematopoietic cells, but little is known about their antigen specificity and potential antileukemia effects.
Lepore, Marco, Locatelli, Franco, Giulia Casorati, Paul Jenö, Chengfeng Xia, Consonni, Michela, S. R. Gundimeda, P. Jeno, Daniela Montagna, C. Bonini, Alessandra Forcina, G. Casorati, Claudia de Lalla, Franco Locatelli, Sansano, Sebastiano, Bonini, Chiara, Piccolo, Francesco, Xia, Chengfeng, Z. Li, P. Dellabona, Garavaglia, Claudio, H. Gsellinger, F. Piccolo, de Lalla, Claudia, Paolo Dellabona, G. Ni, F. Ciceri, Gundimeda, S. Ramanjaneyulu, Heiko Gsellinger, Häussinger, Daniel, Daniel Häussinger, Scelfo, Andrea, L. Mori, C. Garavaglia, Gennaro De Libero, A. Bondanza, Michela Consonni, Sebastiano Sansano, A. Forcina, Ciceri, Fabio, Jenö, Paul, Fabio Ciceri, M. Lepore, Attilio Bondanza, Gsellinger, Heiko, De Libero, Gennaro, S. Sansano, Bondanza, Attilio, Casorati, Giulia, D. Haussinger, Marco Lepore, C. de Lalla, G. De Libero, M. Consonni, Guanghui Ni, Lucia Mori, Li, Zhiyuan, Zhiyuan Li, Montagna, Daniela, Forcina, Alessandra, Andrea Scelfo, Mori, Lucia, S. Ramanjaneyulu Gundimeda, Chiara Bonini, Claudio Garavaglia, A. Scelfo, Francesco Piccolo, Ni, Guanghui, C. Xia, Dellabona, Paolo   +69 more
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Expression of an anti-CD33 single-chain antibody by Pichia pastoris [PDF]

, 2005
CD33 is a cell surface glycoprotein expressed on cells of myelomonocytic lineage, leukaemic cells, but not haematopoietic stem cells. By virtue of its expression pattern, CD33 has become a popular target for new immunotherapeutic approaches to treat ...
Nicholls, Peter J., Blower, Philip J., Peter J. Nicholls, Trivett, Amanda J., Blower, P J, Emberson, L M, Philip J. Blower, Nicholls, P J, Amanda J. Trivett, Louise M. Emberson, Emberson, Louise M., Trivett, A J   +11 more
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Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. [PDF]

, 2012
Dendritic cell (DC) and natural killer (NK) cell interactions are important for the regulation of innate and adaptive immunity, but their relevance during early pregnancy remains elusive.
Irene Tirado-González, Gabriela Barrientos, Winterhager Elke, Barrientos Gabriela, Petra von Kwiatkowski (130217), Victor L. J. L. Thijssen (130213), Petra von Kwiatkowski, Burghard F. Klapp (130219), Blois, Sandra M., von Kwiatkowski, P., von Kwiatkowski Petra, Gabriela Barrientos (130201), Irene Tirado González (130195), González, I.T., Petra Moschansky (130215), Freitag, Nancy, Victor L J L Thijssen, Elke Winterhager (130222), González Irene Tirado, Klapp, Burghard F., Petra Moschansky, Freitag, N., Teresa Otto (130209), Tirado González, Irene, Nancy Freitag (130205), Gonzalez, Irene T., Barrientos, Gabriela, Bauersachs, Stefan, Nancy Freitag, Blois, S.M., Elke Winterhager, von Kwiatkowski, Petra, Thijssen, V.L.J.L., Freitag Nancy, Kwiatkowski, Petra von, Winterhager, E., Thijssen Victor L. J. L., Stefan Bauersachs (130224), Sandra M. Blois (130225), Bauersachs Stefan, Otto Teresa, Klapp, B.F., Moschansky, P., Stefan Bauersachs, Moschansky Petra, Thijssen, Victor L., Bauersachs, S., Teresa Otto, Klapp Burghard F., Barrientos, G., Burghard F Klapp, Barrientos, Gabriela Laura, Winterhager, Elke, Thijssen, Victor L. J. L., Moschansky, Petra, Otto, Teresa, Otto, T., Blois Sandra M., Sandra M Blois   +58 more
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Assessing the response of T cells to "Mycobacterium tuberculosis" lipids [PDF]

, 2008
Most vaccines used nowadays are created using inactivated or attenuated compounds from micro-organisms. Advances in basic immunology and molecular biology opened the gate for consequent improvement of vaccination strategies.
Collmann, Anthony
core   +1 more source

Expression of myeloid differentiation antigens on normal and malignant myeloid cells

, 1981
been characterized that define four surface antigens (MY3, MY4, MY7, and MY8) of human myeloid cells. They were derived from a fusion of the NS-1 plasmacytoma cell line with splenocytes from a mouse immunized with human acute myelomonocytic leukemia ...
L M Nadler, J Ritz, Lee M. Nadler, James D. Griffin, Jerome Ritz, J D Griffin, Stuart F. Schlossman, S F Schlossman   +7 more
core   +1 more source

Selective expression of fos proto-oncogene in human acute myelomonocytic and monocytic leukemias: A molecular marker of terminal differentiation

, 1987
Expression of human fos proto-oncogene (c-fos) was analyzed in primary cells from 50 untreated acute lymphocytic (ALL) and myeloblastic (AML) leukemias.
Pelosi E., Peschle C., Mandelli F., Mavilio F., Sposi N. M., Petrini M., Bordignon C., Testa U., Amadori S.   +8 more
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Summary of workshop findings for porcine myelomonocytic markers

, 2001
About 65 monoclonal antibodies (mAb) including 17 internal controls were analyzed for their ability to recognize and bind to various cells of the myelomonocytic lineage.
Domínguez, Javier, Sinkora, J., Lunney, J. K., McCullough, Kenneth C., Ezquerra Martínez, Ángel, Haverson, K., Alonso, Fernando, Thacker, E., Summerfield, A.   +8 more
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Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source