Results 81 to 90 of about 214,371 (284)
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Advanced Healthcare Materials, EarlyView.Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source
Journal of Extracellular VesiclesSeminal plasma induces immune tolerance towards paternal allogenic antigens within the female reproductive tract and during foetal development. Recent evidence suggests a role for extracellular vesicles in seminal plasma (spEVs).
Xiaogang Zhang +8 more
doaj +1 more source
IL‐2 Free Expansion of T Cells with Immunofilaments
Advanced Healthcare Materials, EarlyView.Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Сибирский онкологический журнал, 2016 Currently, cellular immunity can be estimated using the cluster of differentiation antigens or CD-markers. The panel of CD-markers including 6-8 parameters is usually used for assessment of cellular immunity.
E. V. Abakushina +5 more
doaj
The development and function of dendritic cell populations and their regulation by miRNAs
Protein & Cell, 2017 Dendritic cells (DCs) are important immune cells linking innate and adaptive immune responses. DCs encounter various self and non-self antigens present in the environment and induce different types of antigen specific adaptive immune responses.
Haibo Zhou, Li Wu
doaj +1 more source
Advanced Healthcare Materials, EarlyView.HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu +21 more
wiley +1 more source
Advanced Materials, EarlyView.We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam +5 more
wiley +1 more source
Mediators of Inflammation, 2019 Dendritic cells (DCs) are the most efficient antigen-presenting cells and link the innate immune sensing of the environment to the initiation of adaptive immune responses, which may be directed to either acceptance or elimination of the recognized ...
Ana Paula Silva de Azevedo-Santos +8 more
doaj +1 more source
T-lymphocyte differentiation is accompanied by increase in sialic acid content of Thy-1 antigen
Nature, 1980 Lymphocyte differentiation is accompanied by changes in the expression of various glycoproteins at the cell surface 1–4. Whether changes in the structures of individual glycoproteins, as opposed to changes in then expression, also occur during this differentiation is not known.
Hoessli, D, Bron, C, Pink, J R
openaire +3 more sources