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CRISPR-screen informed engineered T cell therapies. [PDF]
Wong K, Calnan C, Benson MJ.
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Immunodominance is a poor predictor of vaccine-induced T follicular helper cell quality. [PDF]
Zheng MZM +9 more
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Senescent Cell Antigen: A Terminal Differentiation Antigen
Survey and Synthesis of Pathology Research, 2008Investigations into mechanisms by which macrophages distinguish mature from senescent self cells revealed that a approximately 62,000 Mr glycoprotein, the senescent cell antigen, a terminal differentiation antigen, appears on the surface of senescent and damaged cells. It is recognized by the antigen-binding Fab region of a specific IgG autoantibody in
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Differentiation Antigens and Macrophage Heterogeneity
1982The macrophage provides a favorable system to study differentiation in eukaryotic cells. Multipotential hemopoietic precursors proliferate and differentiate in response to ill-defined signals and are then widely distributed via the blood stream as mature members of the “Mononuclear Phagocyte System”.
S, Gordon, S, Hirsch
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Serological identification of thymocyte differentiation antigens
Human Immunology, 1988We have examined subfractions of human thymocytes for the expression of novel differentiation antigens. Non-HLA alloantisera procured from multiparous women served as antibody probes. Thymocytes from five individuals were sequentially separated by discontinuous Percoll density gradient centrifugation and a peanut agglutinin (PNA) panning technique ...
S, Park +5 more
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DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS
Annual Review of Immunology, 1997▪ Abstract Studies performed during the past several years make plain that ligand occupancy of antigen receptors need not necessarily provoke identical responses in all instances. For example, ligation of antigen receptors may stimulate a proliferative response, induce a state of unresponsiveness to subsequent stimulation (anergy), or induce apoptosis.
J, Alberola-Ila +3 more
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Differential extraction of antigens of Anaplasma marginale
American Journal of Veterinary Research, 1988SUMMARY Strain-, group-, and genus-specific antigens of the Florida isolate of Anaplasma marginale had different solubilities in zwitterionic, nonionic, and anionic detergents. On the basis of their solubility in nonionic detergent, antigens were grouped into 3 classes: (i) a 108-kilodalton (kD) group-specific antigen and a series of poorly defined ...
J H, Adams, R D, Smith
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Carbohydrate differentiation antigens
Trends in Biochemical Sciences, 1981Abstract Studies with monoclonal antibodies specific for defined carbohydrate sequences have shown that some of the changing antigenicities in the glycoproteins and glycolipids of cells, during successive developmental stages, may be brought about by sequential addition or deletion of monosaccharide residues.
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