Results 241 to 250 of about 371,078 (308)

The resilient subset: cancer stem cells at the core of immunotherapy resistance. [PDF]

open access: yesImmunother Adv
Gajón JA   +6 more
europepmc   +1 more source

Senescent Cell Antigen: A Terminal Differentiation Antigen

Pathology and Immunopathology Research, 1985
Investigations into mechanisms by which macrophages distinguish mature from senescent self cells revealed that a approximately 62,000 Mr glycoprotein, the senescent cell antigen, a terminal differentiation antigen, appears on the surface of senescent and damaged cells. It is recognized by the antigen-binding Fab region of a specific IgG autoantibody in
openaire   +2 more sources

Differentiation Antigens and Macrophage Heterogeneity

1982
The macrophage provides a favorable system to study differentiation in eukaryotic cells. Multipotential hemopoietic precursors proliferate and differentiate in response to ill-defined signals and are then widely distributed via the blood stream as mature members of the “Mononuclear Phagocyte System”.
S, Gordon, S, Hirsch
openaire   +2 more sources

Serological identification of thymocyte differentiation antigens

Human Immunology, 1988
We have examined subfractions of human thymocytes for the expression of novel differentiation antigens. Non-HLA alloantisera procured from multiparous women served as antibody probes. Thymocytes from five individuals were sequentially separated by discontinuous Percoll density gradient centrifugation and a peanut agglutinin (PNA) panning technique ...
S, Park   +5 more
openaire   +2 more sources

DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS

Annual Review of Immunology, 1997
▪ Abstract  Studies performed during the past several years make plain that ligand occupancy of antigen receptors need not necessarily provoke identical responses in all instances. For example, ligation of antigen receptors may stimulate a proliferative response, induce a state of unresponsiveness to subsequent stimulation (anergy), or induce apoptosis.
J, Alberola-Ila   +3 more
openaire   +2 more sources

Carbohydrate differentiation antigens

Trends in Biochemical Sciences, 1981
Abstract Studies with monoclonal antibodies specific for defined carbohydrate sequences have shown that some of the changing antigenicities in the glycoproteins and glycolipids of cells, during successive developmental stages, may be brought about by sequential addition or deletion of monosaccharide residues.
openaire   +1 more source

Differential extraction of antigens of Anaplasma marginale

American Journal of Veterinary Research, 1988
SUMMARY Strain-, group-, and genus-specific antigens of the Florida isolate of Anaplasma marginale had different solubilities in zwitterionic, nonionic, and anionic detergents. On the basis of their solubility in nonionic detergent, antigens were grouped into 3 classes: (i) a 108-kilodalton (kD) group-specific antigen and a series of poorly defined ...
J H, Adams, R D, Smith
openaire   +2 more sources

Monocyte differentiation and antigen-presenting functions

Nature Reviews Immunology, 2017
Monocytes develop in the bone marrow and represent the primary type of mononuclear phagocyte found in the blood. They were long thought of as a source for tissue macrophages, but recent studies indicate more complex roles for monocytes, both within the circulation and after their migration into tissues and lymphoid organs.
Claudia V, Jakubzick   +2 more
openaire   +2 more sources

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