Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody
Frontiers in Microbiology, 2020 Invasive fungal infections (IFI) cause devastating morbidity and mortality, with the number of IFIs more than tripling since 1979. Our laboratories were the first to demonstrate that radiolabeled microorganism-specific monoclonal antibodies are highly ...
Muath Helal +5 more
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Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis. [PDF]
PLoS ONE, 2011 The thermally dimorphic fungus Paracoccidioides brasiliensis (Pb) is the causative agent of paracoccidioidomycosis (PCM), one of the most frequent systemic mycosis that affects the rural population in Latin America.
Karen A Cavassani +11 more
doaj +1 more source
Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.
PLoS Pathogens, 2021 The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as alum ...
Lucas Dos Santos Dias +18 more
doaj +1 more source
IDCases, 2017 Titanium plane screw fixation of the frontal sinus is an approach used by otolaryngologists to obliterate this space in an attempt to reduce sinus infections.
Anthony M. Szema, Cyrus Jo
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Topical Application of Imiquimod as a Treatment for Chromoblastomycosis [PDF]
, 2014 Peer reviewedPublisher ...
Belda Junior, Walter +7 more
core +1 more source
Journal of Fungi, 2020 Paracoccidioidomycosis (PCM) is a life-threatening systemic infection caused by the fungal pathogen Paracoccidioides brasiliensis and related species. Whole-genome sequencing and stage-specific proteomic analysis of Paracoccidioides offer the opportunity
A. M. Rodrigues +5 more
semanticscholar +1 more source
A Model Vaccine Exploiting Fungal Mannosylation to Increase Antigen Immunogenicity [PDF]
The Journal of Immunology, 2005 Abstract Ag mannosylation represents a promising strategy to augment vaccine immunogenicity by targeting Ag to mannose receptors (MRs) on dendritic cells. Because fungi naturally mannosylate proteins, we hypothesized that Ags engineered in fungi would have an enhanced capacity to stimulate T cell responses.
Jennifer S, Lam +3 more
openaire +2 more sources
Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis
Clinical and Developmental Immunology, 2008 Invasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical symptoms and a definitive ...
Ana Laín +5 more
doaj +1 more source
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]
, 2012 Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette +8 more
core +1 more source
Cross-Reactivity of the PLATELIACANDIDAAntigen Detection Enzyme Immunoassay with Fungal Antigen Extracts [PDF]
Journal of Clinical Microbiology, 2003 ABSTRACTWe studied the specificity of the PLATELIACANDIDAAg enzyme immunoassay by using 130 isolates of 63 clinically relevant fungal species. Antigen extracts of sevenCandidaspp. (Candida albicans,C. dubliniensis,C. famata,C. glabrata,C. guilliermondii,C. lusitaniae, andC.
Dagmar, Rimek +2 more
openaire +2 more sources