Results 21 to 30 of about 35,568 (259)
Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody
Frontiers in Microbiology, 2020 Invasive fungal infections (IFI) cause devastating morbidity and mortality, with the number of IFIs more than tripling since 1979. Our laboratories were the first to demonstrate that radiolabeled microorganism-specific monoclonal antibodies are highly ...
Muath Helal +5 more
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Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis. [PDF]
PLoS ONE, 2011 The thermally dimorphic fungus Paracoccidioides brasiliensis (Pb) is the causative agent of paracoccidioidomycosis (PCM), one of the most frequent systemic mycosis that affects the rural population in Latin America.
Karen A Cavassani +11 more
doaj +1 more source
The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis
Vaccines, 2021 Systemic candidiasis is an invasive fungal infection caused by members of the genus Candida. The recent emergence of antifungal drug resistance and increased incidences of infections caused by non-albicans Candida species merit the need for developing ...
Manisha Shukla +2 more
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Structural basis of Blastomyces Endoglucanase-2 adjuvancy in anti-fungal and -viral immunity.
PLoS Pathogens, 2021 The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as alum ...
Lucas Dos Santos Dias +18 more
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Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis
Clinical and Developmental Immunology, 2008 Invasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical symptoms and a definitive ...
Ana Laín +5 more
doaj +1 more source
IDCases, 2017 Titanium plane screw fixation of the frontal sinus is an approach used by otolaryngologists to obliterate this space in an attempt to reduce sinus infections.
Anthony M. Szema, Cyrus Jo
doaj +1 more source
Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis
Frontiers in Immunology, 2022 Pre-term infants in neonatal intensive care units are vulnerable to fungal sepsis. In this patient population, Candida albicans remains the predominant fungal pathogen causing high morbidity and mortality, despite antifungal therapy.
Shakti Singh +6 more
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Outer membrane vesicles (OMVs) and their therapeutic potential as anti-infectious agents
Nano TrendsOuter membrane vesicles (OMVs) derived from Gram-negative bacteria have emerged as promising therapeutic agents for combating infectious diseases. These small, spherical structures carry diverse cargo molecules, including virulence factors, antigens, and
Mariana Ottaiano Gonçalves +4 more
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Wellcome Open Research, 2018 Antibodies against pathogens provide information on exposure to infectious agents and are meaningful measures of past and present infection. Antibodies were measured in the plasma of children that are the offspring in a population-based birth cohort, the
Ruth E. Mitchell +9 more
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CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source