Results 11 to 20 of about 35,568 (259)
Review of current and future therapeutics in ABPA
Therapeutic Advances in Chronic Disease, 2021 Allergic bronchopulmonary aspergillosis is an allergic pulmonary condition caused by hypersensitivity to antigens of Aspergillus sp. found most commonly in patients with underlying asthma or cystic fibrosis.
Elisa Lewington-Gower +2 more
doaj +1 more source
Fungal Antigens Expressed during Invasive Aspergillosis [PDF]
Infection and Immunity, 2005 ABSTRACTRabbits that had been infected intravenously with conidiospores ofAspergillus fumigatuswere used as sources of antibody for screening a λ phage cDNA expression library. The cDNA was derived fromA. fumigatusmRNA that had been extracted from newly formed, germling hyphae. Thirty-six antigens were identified using antisera from six rabbits. Though
Denikus, N. +5 more
openaire +4 more sources
Functional Characterization of Hexacorallia Phagocytic Cells
Frontiers in Immunology, 2021 Phagocytosis is the cellular defense mechanism used to eliminate antigens derived from dysregulated or damaged cells, and microbial pathogens. Phagocytosis is therefore a pillar of innate immunity, whereby foreign particles are engulfed and degraded in ...
Grace A. Snyder +9 more
doaj +1 more source
Germline IgM predicts T cell immunity to Pneumocystis
JCI Insight, 2022 Pneumocystis is the most common fungal pulmonary infection in children under the age of 5 years. In children with primary immunodeficiency, Pneumocystis often presents at 3–6 months of age, a time period that coincides with the nadir of maternal IgG and ...
Kristin Noell +6 more
doaj +1 more source
Vaccines for human fungal diseases: close but still a long way to go
npj Vaccines, 2021 Despite the substantial global burden of human fungal infections, there are no approved fungal vaccines to protect at risk individuals. Here, we review the progress that has been made and the challenges that lie ahead in the quest towards efficacious ...
Lorena V. N. Oliveira +3 more
doaj +1 more source
Discriminating antigen and non-antigen using proteome dissimilarity II: viral and fungal antigens [PDF]
Bioinformation, 2010 Immunogenicity arises via many synergistic mechanisms, yet the overall dissimilarity of pathogenic proteins versus the host proteome has been proposed as a key arbiter. We have previously explored this concept in relation to Bacterial antigens; here we extend our analysis to antigens of viral and fungal origin.
Ramakrishnan, Kamna, Flower, Darren R
openaire +3 more sources
Frontiers in Immunology, 2021 Cryptococcus neoformans, an opportunistic fungal pathogen ubiquitously present in the environment, causes cryptococcal meningitis (CM) mainly in immunocompromised patients, such as AIDS patients.
A. Elisabeth Gressler +11 more
doaj +1 more source
Galactofuranose Antigens, a Target for Diagnosis of Fungal Infections in Humans [PDF]
Future Science OA, 2017 The use of biomarkers for the detection of fungal infections is of interest to complement histopathological and culture methods. Since the production of antibodies in immunocompromised patients is scarce, detection of a specific antigen could be effective for early diagnosis.
Marino, María Carla +2 more
openaire +3 more sources
Use of Urine Antigen Testing for Blastomyces in an Integrated Health System
Journal of Patient-Centered Research and Reviews, 2018 Purpose: Blastomycosis, an endemic fungal infection, mimics many other diseases. We explored the use of Blastomyces urine antigen (BuAg), reportedly the most sensitive noninvasive test, in clinical practice and compared it to other noninvasive tests ...
Dennis J. Baumgardner
doaj +1 more source
A Novel Insight into the Immunologic Basis of Chronic Granulomatous Invasive Fungal Rhinosinusitis
Allergy & Rhinology, 2016 Background Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a rare disease. The underlying immune responses that drive the development of CGIFRS, as opposed to successful pathogen clearance and controlled inflammation, are not currently ...
William Rae M.R.C.P. +8 more
doaj +1 more source