Immunological basis of septal fibrosis of the liver in Capillaria hepatica-infected rats
Rats infected with the helminth Capillaria hepatica regularly develop septal fibrosis of the liver similar to that induced by repeated ip injections of pig serum.
Lemos Q.T. +2 more
doaj
A randomised controlled trial of the effects of albendazole in pregnancy on maternal responses to mycobacterial antigens and infant responses to bacille Calmette-Guérin (BCG) immunisation [ISRCTN32849447] [PDF]
Background: Maternal schistosomiasis and filariasis have been shown to influence infant responses to neonatal bacille Calmette-Guérin (BCG) immunisation but the effects of maternal hookworm, and of de-worming in pregnancy, are unknown.
A Hall +35 more
core +4 more sources
Nitric oxide (NO) is an important effector molecule involved in immune regulation and defense. NO produced by cytokine-activated macrophages was reported to be cytotoxic against the helminth Schistosoma mansoni.
Diana Magalhães de Oliveira +3 more
doaj +1 more source
Mucosal Mast Cells Response in the Jejunum of Ascaridia Galli-Infected Laying Hens [PDF]
Intestinal defense mechanism against helminthes parasitic nematode to be associated with mucosal mast cells reaction. The aim of this research was to examine the effect of infection by Ascaridia galli parasite to trigger mucosal defense based on mucosal ...
Balqis, U. (U) +4 more
core
Hypertension persisting after pre-eclampsia: a prospective cohort study at Mulago Hospital, Uganda. [PDF]
BACKGROUND: Pre-eclampsia/eclampsia usually resolves after delivery but sometimes hypertension persists and cardiovascular disease develops later. Our objective was to determine the incidence and maternal socio-demographic and obstetric risk factors for ...
A Moffett +58 more
core +2 more sources
Patent Landscape of Helminth Vaccines and Related Technologies [PDF]
Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths.
Burke, Rayna +4 more
core +1 more source
Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans [PDF]
With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective.
Antonopoulos, A. +8 more
core +3 more sources
BackgroundSchistosomiasis is a disease of major public health importance in sub-Saharan Africa. Immunoregulation begins early in schistosome infection and is characterized by hyporesponsiveness to parasite and bystander antigens, suggesting that a ...
Diana K Riner +9 more
doaj +1 more source
Uptake of three doses of HPV vaccine by primary school girls in Eldoret, Kenya : a prospective cohort study in a malaria endemic setting [PDF]
Background: All women are potentially at risk of developing cervical cancer at some point in their life, yet it is avoidable cause of death among women in Sub- Saharan Africa with a world incidence of 530,000 every year.
Kirop, Elijah +8 more
core +3 more sources
Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]
In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Adams +80 more
core +1 more source

