Results 81 to 90 of about 20,135 (182)

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

Hybridization and Immunology in Animals: A Review

Ecology and Evolution, Volume 16, Issue 4, April 2026.
Hybridization can reshape immune function by introducing novel genetic variation and combining parental immune traits. Across animal taxa, this process may influence resistance, tolerance, and pathogen dynamics, with important implications for disease ecology and One Health.
Cheyenne R. Graham, Cody W. Thompson, Delbert A. Green II, Kelly A. Speer   +3 more
wiley   +1 more source

IL-10 production in macrophages is regulated by a TLR-driven CREB-mediated mechanism that is linked to genes involved in cell metabolism [PDF]

, 2015
IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections, macrophages are an important source of IL-10; however, the molecular mechanism underpinning production of IL-10 by ...
Mountford, Adrian P., Prendergast, Catriona T., Sanin, David E.   +2 more
core   +1 more source

Immuno-therapeutic and prophylactic potential of Trichinella spiralis antigens for inflammatory bowel diseases

Food and Waterborne Parasitology
Ulcerative colitis (UC), a severe chronic inflammatory disorder of the colon, is one of the inflammatory bowel diseases (IBD) that affects humans and several domestic animal species, including cats and dogs.
Majed H. Wakid, Walaa A. El Kholy, Muslimah N. Alsulami, Eman S. El-Wakil   +3 more
doaj   +1 more source

The Potential of Bioinformatics in Revolutionizing Disease Diagnosis in Sub‐Saharan Africa: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Despite its role in healthcare delivery and accessibility, the potential of bioinformatics to transform disease diagnosis in SSA remains unknown. This narrative review aims to assess the current status of bioinformatics initiatives in SSA and evaluate the role of bioinformatics in transforming diagnosis of major diseases in ...
Wilfred Ofosu, Fleischer C. N. Kotey, Alex Odoom, Onyansaniba K. Ntim, Eric S. Donkor   +4 more
wiley   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission. [PDF]

, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Arnold, Benjamin F, Lammie, Patrick J, Priest, Jeffrey W, Scobie, Heather M   +3 more
core   +1 more source

The impact of prenatal exposure to parasitic infections and to anthelminthic treatment on antibody responses to routine immunisations given in infancy: Secondary analysis of a randomised controlled trial.

PLoS Neglected Tropical Diseases, 2017
BackgroundChronic parasitic infections are associated with active immunomodulation which may include by-stander effects on unrelated antigens. It has been suggested that pre-natal exposure to parasitic infections in the mother impacts immunological ...
Stephen Nash, Alexander J Mentzer, Swaib A Lule, Dennison Kizito, Gaby Smits, Fiona R M van der Klis, Alison M Elliott   +6 more
doaj   +1 more source

Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the conservation conditions of foods made with eggs or egg products in retail establishments

Food Risk Assess Europe, Volume 4, Issue 2, April 2026.
Abstract Royal Decree 1021/2022, which regulates certain hygiene requirements for the production and marketing of foodstuffs in retail establishments, establishes that, in retail establishments, food made with raw egg subjected to heat treatment where a temperature equal to or greater than 70°C is reached for 2 seconds in the centre of the product or ...
Antonio Valero Díaz, María Dolores Rodrigo Aliaga, Rosa María Capita González, Baltasar Mayo Pérez, Azucena del Carmen Mora Gutiérrez, Fernando Pérez Rodríguez, Paula Arrabal Durán   +6 more
wiley   +1 more source

Cellular networks controlling Th2 polarization in allergy and immunity [PDF]

, 2012
In contrast to the development of Th1 (type 1 T helper cells), Th17 and Treg (regulatory T cells), little is known of the mechanisms governing Th2 development, which is important for immunity to helminths and for us to understand the pathogenesis of ...
Kool, Mirjam, Hammad, Hamida, Lambrecht, Bart   +2 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source