Results 81 to 90 of about 195,323 (225)

Building an Interleukin‐10‐Producing Identity: How B Cells Acquire Interleukin‐10 Competence and How Plasma Cell Differentiation Consolidates This Program

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Interleukin (IL)‐10‐producing B cells represent an archetype for the regulatory functions of B cells. Here, we review the cell‐surface receptors and transcriptional regulators that control IL‐10 expression in B cells and enable their regulatory function in vivo.
Bui Thi Cuc, Yanli Tong, Zhiguo Wu, Daniel Alvarez‐Simon, Simon Fillatreau   +4 more
wiley   +1 more source

Transmission of helminth eggs through hands in a high-risk community.

, 2014
BACKGROUND: The role that hands play in the transmission of Ascaris is not well understood. METHODS: A newly developed method to quantify the presence helminth eggs on hands was tested among a group of farmers in Vietnam.
Do, Hong Anh, Ensink, Jeroen HJ, Jeandron, Aurelie, Nguyen, Viet Anh, Gulliver, Francesca   +4 more
core   +1 more source

How long can stool samples be fixed for an accurate diagnosis of soil-transmitted helminth infection using mini-FLOTAC? [PDF]

, 2015
Kato-Katz is a widely used method for the diagnosis of soil-transmitted helminth infection. Fecal samples cannot be preserved, and hence, should be processed on the day of collection and examined under a microscope within 60 min of slide preparation ...
Shaali M Ame, Giuseppe Cringoli, Jennifer Keiser, Utzinger, Jürg, Ame, Shaali M, Speich, Benjamin, Benjamin Speich, Burioni, Roberto, Marco Albonico, Ianniello, Davide, Antonio Montresor, Rinaldi, Laura, Beatrice Barda, Keiser, Jennifer, Montresor, Antonio, Roberto Burioni, Ame, Shaali M., Davide Ianniello, Albonico, Marco, Laura Rinaldi, Jürg Utzinger, Barda, Beatrice, Cringoli, Giuseppe   +22 more
core   +1 more source

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.

PLoS Computational Biology, 2015
Allergic reactions can be considered as maladaptive IgE immune responses towards environmental antigens. Intriguingly, these mechanisms are observed to be very similar to those implicated in the acquisition of an important degree of immunity against ...
Nidhi Tyagi, Edward J Farnell, Colin M Fitzsimmons, Stephanie Ryan, Edridah Tukahebwa, Rick M Maizels, David W Dunne, Janet M Thornton, Nicholas Furnham   +8 more
doaj   +1 more source

Vaccination With Trichuris muris Poly‐Cysteine and Histidine‐Tailed Protein p43 Protects Against Chronic Infection

Parasite Immunology, Volume 48, Issue 10, October 2026.
ABSTRACT Trichuris trichiura is one of the soil transmitted geohelminths which together currently affect approximately 25% of the global population resulting in considerable morbidity particularly in children and young adults. Recent estimates put infection by T. trichiura at approximately 513 million.
Allison J. Bancroft, Kelly S. Hayes, Laura Campbell, Seona Thompson, Christina Dold, Luke Blackwell, Christine S. Rollier, David J. Thornton, Richard K. Grencis   +8 more
wiley   +1 more source

Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]

, 2012
Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
Isabella M. Cattadori, Réka Albert (31571), Juilee Thakar (31567), Albert Réka, Ashutosh K Pathak, Lisa Murphy, Ashutosh K. Pathak, Albert, R., Ashutosh K. Pathak (188188), Cattadori Isabella M., Pathak, A.K., Thakar, J., Juilee Thakar, Murphy Lisa, Thakar Juilee, Cattadori, I.M., Lisa Murphy (188192), Réka Albert, Pathak Ashutosh K., Isabella M. Cattadori (130510), Isabella M Cattadori, Murphy, L.   +21 more
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, Volume 16, Issue 9, Page 1708-1725, September 2026.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
Josiah I. Chung, Nutman, Thomas B, Barnes, MA, Josiah I Chung, Chung, Josiah I, Cooper, Philip J, Meera G. Nair (285902), Josiah I. Chung (682394), Nair, Meera G, Gang Chen (107840), Thomas B. Nutman, Nair, MG, Mali Camberis, Le Gros, G, Graham Le Gros, Mark A. Barnes (682393), Thomas B. Nutman (113195), Le Gros, Graham, Steel, C, Mark A Barnes, Jessica C. Jang (682391), Mitchell A. Lazar, Camberis, M, Thomas B Nutman, Meera G. Nair, Cathy Steel (180788), Jang, JC, Meera G Nair, Graham Le Gros (682396), Cooper, PJ, Jessica C Jang, Spencer H. Wang, Lazar, MA, Mitchell A Lazar, Spencer H. Wang (682392), Lazar, Mitchell A, Mark A. Barnes, Chen, Gang, Camberis, Mali, Mitchell A. Lazar (27888), Wang, SH, Gang Chen, Barnes, Mark A, Chen, G, Spencer H Wang, Philip J. Cooper, Wang, Spencer H, Mali Camberis (682395), Philip J. Cooper (218309), Chung, JI, Nutman, TB, Cathy Steel, Jang, Jessica C, Philip J Cooper, Steel, Cathy, Jessica C. Jang   +55 more
core   +1 more source

The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection

Cell Reports, 2018
Summary: Inflammasomes promote immunity to microbial pathogens by regulating the function of IL-1-family cytokines such as IL-18 and IL-1β. However, the roles for inflammasomes during parasitic helminth infections remain unclear. We demonstrate that mice
Rafid Alhallaf, Zainab Agha, Catherine M. Miller, Avril A.B. Robertson, Javier Sotillo, John Croese, Matthew A. Cooper, Seth L. Masters, Andreas Kupz, Nicholas C. Smith, Alex Loukas, Paul R. Giacomin   +11 more
doaj   +1 more source

Intestinal Epithelial Memory: From Inflammatory Imprinting to Metabolite‐Shaped Immune Tolerance

Barrier Immunity, Volume 2, Issue 3, Page 119-130, September 2026.
ABSTRACT Intestinal epithelial cells are rapidly renewing barrier cells that maintain compartmentalization between the luminal environment and the mucosal immune system through epithelial transport, antimicrobial defense, secretory programs, and cytokine‐mediated communication.
Wenjing Yang, Tianming Yu, Yingzi Cong
wiley   +1 more source