Results 61 to 70 of about 20,135 (182)

CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10 [PDF]

open access: yes, 2015
The effect that multiple percutaneous exposures to Schistosoma larvae has on the development of early CD4+ lymphocyte reactivity is unclear, yet it is important in the context of humans living in areas where schistosomiasis is endemic.
Cook, Peter C.   +3 more
core   +1 more source

IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Th9 cells are a subset of CD4+ T cells that express the protoypical cytokine, IL-9. Th9 cells are known to effect protective immunity in animal models of intestinal helminth infections.
Rajamanickam Anuradha   +7 more
doaj   +1 more source

Life Course Malaria Exposure and SARS‐CoV‐2 Seroepidemiology in Ugandan Adolescents: A Longitudinal Study Nested in a Birth Cohort

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya   +22 more
wiley   +1 more source

Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
One-third of the human population is infected with parasitic worms. To avoid being eliminated, these parasites actively dampen the immune response of their hosts.
Irma Haben   +2 more
doaj   +1 more source

Plasmodium falciparum and Helminth Coinfections Increase IgE and Parasite-Specific IgG Responses

open access: yesMicrobiology Spectrum, 2021
Coinfection with Plasmodium falciparum and helminths may impact the immune response to these parasites because they induce different immune profiles. We studied the effects of coinfections on the antibody profile in a cohort of 715 Mozambican children ...
Rebeca Santano   +27 more
doaj   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

open access: yesJournal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor   +4 more
wiley   +1 more source

Description of a new actinosporean type from South African freshwater [PDF]

open access: yes, 2004
The 1st report on actinospores described these organisms as parasites related to myxosporeans. For a long time this group of parasites was believed to represent an independent taxonomic entity.
Avenant-Oldewage, Annemarie   +2 more
core   +1 more source

CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]

open access: yes, 2020
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam   +6 more
core   +1 more source

Recognition Pattern of the Fasciola hepatica Excretome/Secretome during the Course of an Experimental Infection in Sheep by 2D Immunoproteomics

open access: yesPathogens, 2021
Excretory/secretory products released by helminth parasites have been widely studied for their diagnostic utility, immunomodulatory properties, as well as for their use as vaccines.
David Becerro-Recio   +8 more
doaj   +1 more source

Innate Lymphoid Cells in Tissue Homeostasis and Diseases

open access: yesMedComm, Volume 7, Issue 5, May 2026.
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan   +7 more
wiley   +1 more source

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