Results 61 to 70 of about 20,135 (182)
CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10 [PDF]
The effect that multiple percutaneous exposures to Schistosoma larvae has on the development of early CD4+ lymphocyte reactivity is unclear, yet it is important in the context of humans living in areas where schistosomiasis is endemic.
Cook, Peter C. +3 more
core +1 more source
IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection. [PDF]
Th9 cells are a subset of CD4+ T cells that express the protoypical cytokine, IL-9. Th9 cells are known to effect protective immunity in animal models of intestinal helminth infections.
Rajamanickam Anuradha +7 more
doaj +1 more source
ABSTRACT Background COVID‐19 has had major global health impacts, yet reported morbidity and mortality have been lower in Africa despite serological evidence of widespread infection. Malaria has been proposed as a potential modifier of susceptibility to and outcomes of SARS‐CoV‐2 infection.
Ludoviko Zirimenya +22 more
wiley +1 more source
Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection. [PDF]
One-third of the human population is infected with parasitic worms. To avoid being eliminated, these parasites actively dampen the immune response of their hosts.
Irma Haben +2 more
doaj +1 more source
Plasmodium falciparum and Helminth Coinfections Increase IgE and Parasite-Specific IgG Responses
Coinfection with Plasmodium falciparum and helminths may impact the immune response to these parasites because they induce different immune profiles. We studied the effects of coinfections on the antibody profile in a cohort of 715 Mozambican children ...
Rebeca Santano +27 more
doaj +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source
Description of a new actinosporean type from South African freshwater [PDF]
The 1st report on actinospores described these organisms as parasites related to myxosporeans. For a long time this group of parasites was believed to represent an independent taxonomic entity.
Avenant-Oldewage, Annemarie +2 more
core +1 more source
CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam +6 more
core +1 more source
Excretory/secretory products released by helminth parasites have been widely studied for their diagnostic utility, immunomodulatory properties, as well as for their use as vaccines.
David Becerro-Recio +8 more
doaj +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
wiley +1 more source

