Results 41 to 50 of about 195,323 (225)

Helminth Antigens Modulate TLR-Initiated Dendritic Cell Activation [PDF]

The Journal of Immunology, 2004
Abstract There is increasing awareness that helminth infections can ameliorate proinflammatory conditions. In part, this is due to their inherent ability to induce Th2 and, perhaps, regulatory T cell responses. However, recent evidence indicates that helminths also have direct anti-inflammatory effects on innate immune responses.
Colleen M, Kane, Laura, Cervi, Jie, Sun, Amy S, McKee, Katherine S, Masek, Sagi, Shapira, Christopher A, Hunter, Edward J, Pearce   +7 more
openaire   +2 more sources

Treatment with anthelminthics during pregnancy: what gains and what risks for the mother and child? [PDF]

, 2011
In 1994 and 2002, respectively, the World Health Organisation proposed that treatment for hookworm and schistosomiasis could be provided during pregnancy.
Webb, Emily L, Mpairwe, Harriet, EMILY L. WEBB, MOSES MUWANGA, ROBERT TWEYONGYERE, Tweyongyere, Robert, Muwanga, Moses, HARRIET MPAIRWE, DENNISON KIZITO, Muhangi, Lawrence, PATRICE MAWA, LAWRENCE MUHANGI, Entebbe Mother and Baby Study Team, JULIET NDIBAZZA, Elliott, Alison M, Kizito, Dennison, Ndibazza, Juliet, Mawa, Patrice, ALISON M. ELLIOTT   +18 more
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L., P. J. Cooper, Zaph, C, Cooper, P. J., C. Zaph, Cooper, PJ, Harris, NL, Zaph, C., Cooper, Philip, N. L. Harris   +9 more
core   +1 more source

Strongy Detect: Preliminary Validation of a Prototype Recombinant Ss-NIE/Ss-IR Based ELISA to Detect Strongyloides stercoralis Infection.

PLoS Neglected Tropical Diseases, 2022
BackgroundStrongyloides stercoralis (Ss) is the etiological agent of strongyloidiasis, a neglected tropical disease of global concern. Laboratory diagnosis of strongyloidiasis is most often based on detection of antibodies against antigens in an enzyme ...
William J Sears, Thomas B Nutman
doaj   +1 more source

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]

, 2010
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N., Maizels, R M, Burchmore, R., Y. HARCUS, Mduluza, T., R. M. MAIZELS, Harcus, Y, Turner, C.M.R., R. BURCHMORE, C. M. TURNER, Mutapi, F, Midzi, N, Mutapi, F., Maizels, R.M., Turner, C M, Maizels, RM, N. MIDZI, Harcus, Y., Bourke, C., F. MUTAPI, T. MDULUZA, Turner, CM, Maizels, R. M., Bourke, C, Turner, C. M., Mduluza, T, Burchmore, R.J.S., Burchmore, R, C. BOURKE   +28 more
core   +1 more source

The Influence of Helminth Immune Regulation on COVID-19 Clinical Outcomes: Is it Beneficial or Detrimental?

Infection and Drug Resistance, 2021
Muluneh Ademe,1 Friehiwot Girma2 1Department of Microbiology, Immunology and Parasitology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Department of Pediatrics and Child Health Nursing, School of Health Sciences, College ...
Ademe M, Girma F
doaj  

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People's Republic of China [PDF]

, 2013
Soil-transmitted helminth infections affect tens of millions of individuals in the People's Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of ...
Zhou, Xiao-Nong, Lai, Ying-Si, Utzinger, Jürg, Ying-Si Lai, Xiao-Nong Zhou, Vounatsou, Penelope, Jürg Utzinger, Penelope Vounatsou   +7 more
core   +1 more source

Biology, ecology, and conservation of the Italian hare Lepus corsicanus: a review

Wildlife Biology, EarlyView.
The Italian hare Lepus corsicanus, an endemic lagomorph of Italy, serves as a critical case study in evolutionary biology and conservation. Once taxonomically debated, modern genetic and morphological analyses confirm its status as a distinct Pleistocene lineage restricted to the central‐southern Italian Peninsula and Sicily.
Pierangelo Freschi, Valter Trocchi
wiley   +1 more source