Results 21 to 30 of about 195,323 (225)

The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy and early childhood [ISRCTN32849447]. [PDF]

, 2007
BACKGROUND: Helminths have profound effects on the immune response, allowing long-term survival of parasites with minimal damage to the host. Some of these effects "spill-over", altering responses to non-helminth antigens or allergens.
Quigley, Maria A, Whitworth, JA, Morison, Linda, Namujju, Proscovia B, Kabatereine, N, Quigley, MA, Namujju, PB, Muhangi, L, Kizza, Moses, Muwanga, Moses, Kizza, M, Nampijja, M, Muwanga, M, Muhangi, Lawrence, Nampijja, Margaret, Whitworth, James AG, Quigley, Maria, Ndibazza, J, Elliott, Alison M, Elliott, AM, Morison, L, Ndibazza, Juliet, Whitworth, JAG, Kabatereine, Narcis   +23 more
core   +1 more source

Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses

BMC Infectious Diseases, 2008
Background The overlapping geographical and socio-economic distribution of malaria and helminth infection has led to several studies investigating the immunological and pathological interactions of these parasites.
Mduluza T, Cavanagh DR, Magkrioti C, Reilly L, Mutapi F   +4 more
doaj   +1 more source

Associations between mild-to-moderate anaemia in pregnancy and helminth, malaria and HIV infection in Entebbe, Uganda. [PDF]

, 2007
It is suggested that helminths, particularly hookworm and schistosomiasis, may be important causes of anaemia in pregnancy. We assessed the associations between mild-to-moderate anaemia (haemoglobin >8.0 g/dl and
Nabulime, Juliet, Patrick Woodburn, Omoding, Nicholas, Kizito, D, Morison, LA, Muhangi, Lawrence, Lawrence Muhangi, Alison M. Elliott, Mildred Omara, Juliet Nabulime, Elliott, Alison M, Kizito, Dennison, Elliott, AM, Nicholas Omoding, Nabulime, J, Mpairwe, Harriet, Ameke, C, Woodburn, Patrick, Elliott, Alison M., Muhangi, L, Morison, Linda A., Ameke, Christine, Ornoding, N, Mpairwe, H, Woodburn, P, Morison, Linda A, Dennison Kizito, Omara, M, Omara, Mildred, Christine Ameke, Harriet Mpairwe, Linda A. Morison   +31 more
core   +2 more sources

Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. [PDF]

, 2012
BACKGROUND: Plasmodium-helminth coinfection can have a number of consequences for infected hosts, yet our knowledge of the epidemiology of coinfection across multiple settings is limited.
Pullan, Rachel L, Pullan, RL, Kolaczinski, JH, Kolaczinski, Jan H, Snow, RW, Brooker, Simon J, Ashton, Ruth A, Snow, Robert, Kabatereine, NB, Kabatereine, Narcis B, Gitonga, Caroline W, Brooker, SJ, Snow, Robert W, Ashton, RA, Gitonga, CW   +14 more
core   +1 more source

Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells. [PDF]

, 2009
Infection of the mammalian host by the parasitic helminth Schistosoma mansoni is accompanied by the release of excretory/secretory molecules (ES) from cercariae which aid penetration of the skin.
Ross A Paveley, Ross A. Paveley, Adrian P. Mountford, Aynsley, Sarah A, Sarah A. Aynsley, Cook, Peter C, Adrian P Mountford, Turner, Joseph D, Sarah A Aynsley, Paveley Ross A., Paveley, Ross A, Peter C. Cook, Cook, Peter C; id_orcid, Peter C Cook, Cook Peter C., Mountford Adrian P., Joseph D Turner, Joseph D. Turner, Aynsley Sarah A., Mountford, Adrian P, Turner Joseph D.   +20 more
core   +2 more sources

Helminth species-specific effects on IFN-γ producing T cells during active and latent tuberculosis.

PLoS Neglected Tropical Diseases, 2023
BackgroundInterferon-γ (IFN-γ) is a key cytokine inducing protective immune responses during tuberculosis (TB) infection. Helminth-induced immune responses may affect IFN-γ production by T cells, although its connection with disease severity and immune ...
Amare Kiflie, Gezahegn Bewket, Fitsumbrhan Tajebe, Ebba Abate, Thomas Schӧn, Robert Blomgran   +5 more
doaj   +1 more source

Immunoblotting Identification of Diagnostic Antigens of Paragonimus westermani Type 1 for the Detection of Human Pulmonary Paragonimiasis in North East India

Tropical Medicine and Infectious Disease, 2023
Human pulmonary paragonimiasis, an emerging concern in North East India, frequently masquerades as pulmonary tuberculosis due to clinical and radiological similarities, leading to diagnostic challenges.
Kangjam Rekha Devi, Archana Deka, Debdutta Mukherjee, Harpreet Kaur, Kanwar Narain   +4 more
doaj   +1 more source

Does treatment of intestinal helminth infections influence malaria? Background and methodology of a longitudinal study of clinical, parasitological and immunological parameters in Nangapanda, Flores, Indonesia (ImmunoSPIN Study)

BMC Infectious Diseases, 2010
Background Given that helminth infections are thought to have strong immunomodulatory activity, the question whether helminth infections might affect responses to malaria antigens needs to be addressed.
Sutanto Inge, Wahyuni Sitti, Djuardi Yenny, Wibowo Heri, Uh Hae, Ariawan Iwan, Lell Bertrand, Wammes Linda J, Hamid Firdaus, Prasetyani Margaretta A, Wiria Aprilianto E, May Linda, Luty Adrian JF, Verweij Jaco J, Sartono Erliyani, Yazdanbakhsh Maria, Supali Taniawati   +16 more
doaj   +1 more source

ICOS controls Foxp3+ regulatory T-cell expansion, maintenance, and IL-10 production during helminth infection [PDF]

, 2012
Foxp3+ regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity ...
van der Werf, Nienke, MacDonald, Andrew, Redpath, Stephen A, Taylor, Matthew, Cervera, Ana M, Macdonald, Andrew S; id_orcid, Cervera, Ana, Taylor, Matthew D., Maizels, Rick M, Andrew S. MacDonald, Cervera, Ana M., Gray, David, Maizels, Rick, Stephen A. Redpath, Maizels, Rick M., Taylor, Matthew D, Macdonald, Andrew S.; id_orcid, Redpath, Stephen A., Matthew D. Taylor, Rick M. Maizels, David Gray, Nienke van der Werf, Ana M. Cervera   +22 more
core   +1 more source

Helminth parasites and immune regulation [version 1; referees: 2 approved]

F1000Research, 2018
Helminth parasites are complex metazoans that belong to different taxonomic families but that collectively share the capacity to downregulate the host immune response directed toward themselves (parasite-specific immunoregulation).
Pedro H. Gazzinelli-Guimaraes, Thomas B. Nutman   +1 more
doaj   +1 more source