Results 21 to 30 of about 9,987 (185)
BMC Infectious Diseases, 2010 Background Given that helminth infections are thought to have strong immunomodulatory activity, the question whether helminth infections might affect responses to malaria antigens needs to be addressed.
Sutanto Inge +16 more
doaj +1 more source
Helminth parasites and immune regulation [version 1; referees: 2 approved]
F1000Research, 2018 Helminth parasites are complex metazoans that belong to different taxonomic families but that collectively share the capacity to downregulate the host immune response directed toward themselves (parasite-specific immunoregulation).
Pedro H. Gazzinelli-Guimaraes +1 more
doaj +1 more source
Impact of Helminth Infections during Pregnancy on Vaccine Immunogenicity in Gabonese Infants
Vaccines, 2020 Helminth infections are common in sub-Saharan Africa. Besides direct clinical effects, a bias towards a T helper type 2 (Th2) cell immune response is observed.
Judith Flügge +14 more
doaj +1 more source
Helminth infections coincident with active pulmonary tuberculosis inhibit mono- and multifunctional CD4+ and CD8+ T cell responses in a process dependent on IL-10. [PDF]
PLoS Pathogens, 2014 Tissue invasive helminth infections and tuberculosis (TB) are co-endemic in many parts of the world and can trigger immune responses that might antagonize each other.
Parakkal Jovvian George +6 more
doaj +1 more source
A Comparative Analysis of the Protein Cargo of Extracellular Vesicles from Helminth Parasites
Life, 2023 Helminth parasites cause debilitating—sometimes fatal—diseases in humans and animals. Despite their impact on global health, mechanisms underlying host–parasite interactions are still poorly understood.
María Eugenia Ancarola +6 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2012 Multiple sclerosis (MS) is an inflammatory autoimmune demyelinating disease affecting the Central Nervous System, in which Th1 and Th17 cells appear to recognize and react against certain myelin sheath components.Epidemiological evidence has accumulated ...
Jorge eCorreale, Mauricio Franco Farez
doaj +1 more source
PLoS Neglected Tropical Diseases, 2021 BackgroundHelminths can modulate the host immune response to Plasmodium falciparum and can therefore affect the risk of clinical malaria. We assessed here the effect of helminth infections on both the immunogenicity and efficacy of the GMZ2 malaria ...
Odilon Nouatin +24 more
doaj +1 more source
Frontiers in Immunology, 2014 Nearly one quarter of the world’s population is infected with helminth parasites. A common feature of helminth infections is the manifestation of a type 2 immune response, characterized by T helper 2 (Th2) cells that mediate anti-helminth immunity.
Leonie eHussaarts +3 more
doaj +1 more source
Helminth allergens, parasite-specific IgE and its protective role in human immunity
Frontiers in Immunology, 2014 The Th2 immune response, culminating in eosinophilia and IgE production, is not only characteristic of allergy but also of infection by parasitic worms (helminths).
Colin Matthew Fitzsimmons +2 more
doaj +1 more source
Helminth Antigens Modulate TLR-Initiated Dendritic Cell Activation [PDF]
The Journal of Immunology, 2004 Abstract There is increasing awareness that helminth infections can ameliorate proinflammatory conditions. In part, this is due to their inherent ability to induce Th2 and, perhaps, regulatory T cell responses. However, recent evidence indicates that helminths also have direct anti-inflammatory effects on innate immune responses.
Colleen M, Kane +7 more
openaire +2 more sources