Results 11 to 20 of about 20,135 (182)

Helminth species specific expansion and increased TNF-alpha production of non-classical monocytes during active tuberculosis.

open access: yesPLoS Neglected Tropical Diseases, 2021
Both Mycobacterium tuberculosis infection and helminths may affect innate immune mechanisms such as differential effects on monocytes towards the non-classical and intermediate subsets that favor bacterial persistence.
Gezahegn Bewket   +5 more
doaj   +1 more source

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]

open access: yes, 2009
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
Maizels, R M
core   +1 more source

Soil-Transmitted Helminth Vaccines: Are We Getting Closer?

open access: yesFrontiers in Immunology, 2020
Parasitic helminths infect over one-fourth of the human population resulting in significant morbidity, and in some cases, death in endemic countries.
Ayat Zawawi, Kathryn J. Else
doaj   +1 more source

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

open access: yes, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda   +7 more
core   +1 more source

Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice.

open access: yesPLoS ONE, 2022
The world health organization estimates that more than a quarter of the human population is infected with parasitic worms that are called helminths. Many helminths suppress the immune system of their hosts to prolong their survival. This helminth-induced
Wiebke Hartmann   +4 more
doaj   +1 more source

Promising Technologies in the Field of Helminth Vaccines

open access: yesFrontiers in Immunology, 2021
Helminths contribute a larger global burden of disease than both malaria and tuberculosis. These eukaryotes have caused human infections since before our earliest recorded history (i.e.: earlier than 1200 B.C. for Schistosoma spp.).
Dilhan J. Perera   +5 more
doaj   +1 more source

Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]

open access: yes, 2017
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O.   +2 more
core   +1 more source

Effect of treating Schistosoma haematobium infection on Plasmodium falciparum-specific antibody responses

open access: yesBMC Infectious Diseases, 2008
Background The overlapping geographical and socio-economic distribution of malaria and helminth infection has led to several studies investigating the immunological and pathological interactions of these parasites.
Mduluza T   +4 more
doaj   +1 more source

Helminth species-specific effects on IFN-γ producing T cells during active and latent tuberculosis.

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundInterferon-γ (IFN-γ) is a key cytokine inducing protective immune responses during tuberculosis (TB) infection. Helminth-induced immune responses may affect IFN-γ production by T cells, although its connection with disease severity and immune ...
Amare Kiflie   +5 more
doaj   +1 more source

Immunoblotting Identification of Diagnostic Antigens of Paragonimus westermani Type 1 for the Detection of Human Pulmonary Paragonimiasis in North East India

open access: yesTropical Medicine and Infectious Disease, 2023
Human pulmonary paragonimiasis, an emerging concern in North East India, frequently masquerades as pulmonary tuberculosis due to clinical and radiological similarities, leading to diagnostic challenges.
Kangjam Rekha Devi   +4 more
doaj   +1 more source

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