Results 71 to 80 of about 195,323 (225)

Reprogramming macrophages to an anti‐inflammatory phenotype by helminth antigens reduces murine atherosclerosis [PDF]

The FASEB Journal, 2013
Atherosclerosis is a lipid‐driven inflammatory disease of the vessel wall, characterized by the chronic activation of macrophages. We investigated whether the helminth‐derived antigens [soluble egg antigens (SEAs)] could modulate macrophage inflammatory responses and protect against atherosclerosis in mice.
Wolfs, Ine M. J., Stöger, J. Lauran, Goossens, Pieter, Pöttgens, Chantal, Gijbels, Marion J. J., Wijnands, Erwin, van der Vorst, Emiel P. C., van Gorp, Patrick, Beckers, Linda, Engel, David, Biessen, Erik A. L., Kraal, Georg, van Die, Irma, Donners, Marjo M. P. C., de Winther, Menno P. J., Stoger, J.L., Pottgens, C.   +16 more
openaire   +5 more sources

Sustainable control of cyathostomin infections in practice

Equine Veterinary Education, EarlyView.
Summary Cyathostomins are the most prevalent helminths in horses and are found in nearly all grazing groups. These parasites have been shown to exhibit widespread anthelmintic resistance and can cause clinical disease, so they are a growing concern.
J. B. Matthews, T. S. Mair
wiley   +1 more source

Soil-transmitted helminth reinfection after drug treatment : a systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Soil-transmitted helminth (STH) infections (i.e., Ascaris lumbricoides, hookworm, and Trichuris trichiura) affect more than a billion people. Preventive chemotherapy (i.e., repeated administration of anthelmintic drugs to at-risk populations),
Charles H. King (78462), Xiao-Nong Zhou (92570), King Charles H., Sara Melville (165920), King, C. H., Jia, T. W., Utzinger, J., Jürg Utzinger (39609), Zhou Xiao-Nong, Jia Tie-Wu, Sara Melville, Zhou, X. N., Charles H King, Utzinger Jürg, Tie-Wu Jia, Melville, S., Melville Sara, Xiao-Nong Zhou, Jürg Utzinger, Tie-Wu Jia (165917)   +19 more
core   +1 more source

Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection. [PDF]

PLoS Neglected Tropical Diseases, 2014
One-third of the human population is infected with parasitic worms. To avoid being eliminated, these parasites actively dampen the immune response of their hosts.
Irma Haben, Wiebke Hartmann, Minka Breloer   +2 more
doaj   +1 more source

New Insights Into Pathogenesis, Diagnostics, and Therapeutic Options for Canine Angiostrongylosis

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To provide a comprehensive overview of Angiostrongylus vasorum infection in dogs, with a particular emphasis on recent developments in the understanding of disease pathophysiology and an update on developments in diagnostic and therapeutic options.
Iris Elgueta, Daniel Lewis, Eric R. Morgan, Jenny Helm   +3 more
wiley   +1 more source

Helminth infection in southern Laos: high prevalence and low awareness [PDF]

, 2013
BACKGROUND: Helminthiasis is a public health concern in Lao People’s Democratic Republic (Lao PDR, Laos). This study aimed to understand helminth infection and associated risk factors in relation to existing local knowledge, attitudes and practices ...
Xayaseng, Vilavanh, Akkhavong, Kongsap, Vonghachack, Youthanavanh, van Eeuwijk, Peter, Phongluxa, Khampheng, Odermatt, Peter   +5 more
core   +1 more source

Immunodominance, competition and evolution in immunological responses to helminth parasite antigens

Parasitology, 1996
SUMMARYThe paper describes the development and analysis of a mathematical framework for the study of the within-host population dynamics of the interaction between macroparasites and the human immune system. Simple models of this interaction based on the proliferation of T cell clones specific to parasite antigen, and the impact of clonal expansion on ...
D J, Austin, R M, Anderson
openaire   +2 more sources

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

Experimental Physiology, EarlyView.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto, Shigekazu Takemura, Yukiko Minamiyama, Toshikazu Yoshikawa   +3 more
wiley   +1 more source

Suppression of allergic airway inflammation by helminth-induced regulatory T cells [PDF]

, 2005
Allergic diseases mediated by T helper type (Th) 2 cell immune responses are rising dramatically in most developed countries. Exaggerated Th2 cell reactivity could result, for example, from diminished exposure to Th1 cell–inducing microbial infections ...
Lamb, Jonathan, Mark S. Wilson, Adam Balic, Constance A.M. Finney, Taylor, Matthew D, Finney, Constance A, Matthew D. Taylor, Rick M. Maizels, Maizels, Rick, Jonathan R. Lamb, Wilson, Mark A, Balic, Adam   +11 more
core   +1 more source

Nematode in Cockroaches: A Potential Allergen Source

Allergy, EarlyView.
Dongjun Kang, Myung‐hee Yi, Jun Ho Choi, Yun Soo Jang, Seongjun Choe, Ju Yeong Kim   +5 more
wiley   +1 more source