Results 81 to 90 of about 20,110 (228)

Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance [PDF]

, 2012
: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public ...
Bergquist, R., Chen, J. H., Chen, J. X., Tanner, M., Utzinger, J., Wang, H., Zhou, X. N.   +6 more
core   +2 more sources

T follicular helper cells differentiate from Th2 cells in response to helminth antigens [PDF]

Journal of Experimental Medicine, 2009
The relationship of T follicular helper (TFH) cells to other T helper (Th) subsets is controversial. We find that after helminth infection, or immunization with helminth antigens, reactive lymphoid organs of 4get IL-4/GFP reporter mice contain populations of IL-4/GFP-expressing CD4+ T cells that display the TFH markers CXCR5, PD-1, and ICOS.
Zaretsky, Arielle Glatman, Taylor, Justin J., King, Irah L., Marshall, Fraser A., Mohrs, Markus, Pearce, Edward J.   +5 more
openaire   +2 more sources

Helminths as architects of trained tolerance: implications for human health

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz, Jorge Lucas Nascimento Souza, Neima Briggs   +2 more
wiley   +1 more source

The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection

Cell Reports, 2018
Summary: Inflammasomes promote immunity to microbial pathogens by regulating the function of IL-1-family cytokines such as IL-18 and IL-1β. However, the roles for inflammasomes during parasitic helminth infections remain unclear. We demonstrate that mice
Rafid Alhallaf, Zainab Agha, Catherine M. Miller, Avril A.B. Robertson, Javier Sotillo, John Croese, Matthew A. Cooper, Seth L. Masters, Andreas Kupz, Nicholas C. Smith, Alex Loukas, Paul R. Giacomin   +11 more
doaj   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission. [PDF]

, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Arnold, Benjamin F, Lammie, Patrick J, Priest, Jeffrey W, Scobie, Heather M   +3 more
core   +1 more source

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source

Validation of a food frequency questionnaire for children and adolescents aged 4 to 11 years living in Salvador, Bahia.

, 2012
OBJECTIVE: To assess the validity of a food frequency questionnaire (FFQ) by applying it to children and adolescents living in Salvador, Bahia. METHODS: The validity of this FFQ with 98 food items was investigated among 108 children and adolescents who ...
Assis, AMO, Barreto, ML, D'Innocenzo, S, Dourado, LS, Matos, SMA, Oliveira, NS, Prado, MS, Rodrigues, LC, Santos, CAST   +8 more
core   +2 more sources

Helminths in the hygiene hypothesis:Sooner or later? [PDF]

, 2014
There is increasing recognition that exposures to infectious agents evoke fundamental effects on the development and behaviour of the immune system. Moreover, where infections (especially parasitic infections) have declined, immune responses appear to be
Maizels, R. M., Mcsorley, H. J., Smyth, D. J.   +2 more
core   +4 more sources

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, Volume 6, Issue 1, Page 39-50, March 2026.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Immuno-therapeutic and prophylactic potential of Trichinella spiralis antigens for inflammatory bowel diseases

Food and Waterborne Parasitology
Ulcerative colitis (UC), a severe chronic inflammatory disorder of the colon, is one of the inflammatory bowel diseases (IBD) that affects humans and several domestic animal species, including cats and dogs.
Majed H. Wakid, Walaa A. El Kholy, Muslimah N. Alsulami, Eman S. El-Wakil   +3 more
doaj   +1 more source