Results 81 to 90 of about 20,381 (227)
Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]
, 2017 Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O. +2 more
core +1 more source
CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]
, 2020 Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam +6 more
core +1 more source
Immunodominance, competition and evolution in immunological responses to helminth parasite antigens
Parasitology, 1996 SUMMARYThe paper describes the development and analysis of a mathematical framework for the study of the within-host population dynamics of the interaction between macroparasites and the human immune system. Simple models of this interaction based on the proliferation of T cell clones specific to parasite antigen, and the impact of clonal expansion on ...
D J, Austin, R M, Anderson
openaire +2 more sources
The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection
Cell Reports, 2018 Summary: Inflammasomes promote immunity to microbial pathogens by regulating the function of IL-1-family cytokines such as IL-18 and IL-1β. However, the roles for inflammasomes during parasitic helminth infections remain unclear. We demonstrate that mice
Rafid Alhallaf +11 more
doaj +1 more source
T follicular helper cells differentiate from Th2 cells in response to helminth antigens [PDF]
Journal of Experimental Medicine, 2009 The relationship of T follicular helper (TFH) cells to other T helper (Th) subsets is controversial. We find that after helminth infection, or immunization with helminth antigens, reactive lymphoid organs of 4get IL-4/GFP reporter mice contain populations of IL-4/GFP-expressing CD4+ T cells that display the TFH markers CXCR5, PD-1, and ICOS.
Zaretsky, Arielle Glatman +5 more
openaire +2 more sources
Developmental Impact of Maternal Immune Activation on the Fetal Immune System and Lung
European Journal of Immunology, Volume 56, Issue 1, January 2026.Maternal immune activation triggers elevated cytokines (IL‐6 and IL‐17A), disrupting fetal immune system development. This not only alters hematopoietic stem cell balance but also leads to ILC2 hyperactivation in the lung, which could potentially affect susceptibility to allergic diseases in the offspring.
Walaa Jradi +2 more
wiley +1 more source
Parasites & Vectors, 2022 Background There is ample evidence demonstrating a reverse relationship between helminth infection and immune-mediated diseases. Accordingly, several studies have shown that Echinococcus granulosus infection and hydatid cyst compounds are able to ...
Sara Ghabdian +3 more
doaj +1 more source
Structural Determination of a Human IgE Epitope on Major Birch Allergen Bet v 1
Allergy, EarlyView.
Andrea O'Malley +4 more
wiley +1 more source
Parasite excretory-secretory products and their effects on metabolic syndrome [PDF]
, 2017 Obesity, one of the main causes of metabolic syndrome (MetS), is an increasingly common health and economic problem worldwide, and one of the major risk factors for developing type 2 diabetes and cardiovascular disease. Chronic, low-grade inflammation is
Crowe, J. +3 more
core +2 more sources
Integrative Zoology, Volume 21, Issue 1, Page 104-115, January 2026.ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková +7 more
wiley +1 more source