Results 91 to 100 of about 56,164 (204)

Evidence that dengue virus envelope protein in patient platelets originates from infection of megakaryocytic precursors.

PLoS ONE
Dengue virus infection is a major global health problem with clinical outcomes ranging from mild febrile illness to severe disease. Although a reduction in platelet counts is a common feature of dengue, the mechanisms underlying the presence of viral ...
Marcos Alvarado Silva, Tannya Karen Castro Jimenez, Edwin Antonio Lopez Kelly, Nallely Diaz Lima, José Alberto San Juan Luis, Diego Sait Cruz Hernández, Sergio Roberto Aguilar Ruiz, José Bustos Arriaga   +7 more
doaj   +1 more source

Regulated glycosylation patterns of IgG during alloimmune responses against human platelet antigens

, 2009
Various biological activities of immunoglobulin G (IgG) including antibody-dependent cellular cytotoxicity (ADCC) are modulated by the structural features of the N-glycans in the Fc part.
de Haas, Masja, Deelder, André, Kapur, Rick, Wuhrer, Manfred, Koeleman, Carolien A. M., Porcelijn, Leendert, Vidarsson, Gestur   +6 more
core   +1 more source

A machine-learning method for biobank-scale genetic prediction of blood group antigens.

PLoS Computational Biology
A key element for successful blood transfusion is compatibility of the patient and donor red blood cell (RBC) antigens. Precise antigen matching reduces the risk for immunization and other adverse transfusion outcomes.
Kati Hyvärinen, Katri Haimila, Camous Moslemi, Blood Service Biobank, Martin L Olsson, Sisse R Ostrowski, Ole B Pedersen, Christian Erikstrup, Jukka Partanen, Jarmo Ritari   +9 more
doaj   +1 more source

The detection and role of human endogenous retroviruses in multiple sclerosis and other neurological diseases [PDF]

, 2009
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyHuman endogenous retroviruses (HERVs) are estimated to form approximately 5% of the human genome.
Smith, Richard G.
core  

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice

, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A, Owen, JS, Dickson, G, Graham, IR, Harris, JD   +4 more
core  

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents

, 2005
Campetella, O., Rooijen, N. van, Tribulatti, M.V., Mucci, J., Leguizamon, M.S., van Rooijen, N.   +5 more
core   +1 more source

Development of detection kit for anti-platelet antibodies in patients with thrombocytopenia by modified SPRCA

Journal of Associated Medical Sciences, 2008
Detection of anti-platelet alloantibodies in serum of patients with thrombocytopenia is important for helps in diagnosis and investigation as well as specific treatment. Since, platelets provide both common and platelet specific antigens which can induce
Witoon Sriwichai, Jaturaporn Pornsinlapatip, Preeyanat Vongchan   +2 more
doaj  

Polymorphisms of platelet glycoproteins in blood donors from Amazonas

, 2015
Humans platelets Antigens (HPA) are specific alloantigens of platelets resulting from single nucleotide polymorphism (SNP) that lead to substitution of an amino acid protein level defined by polymorphisms of platelet surface glycoproteins.
Portela, Cíntia Nicácio
core  

Human platelet antigen Duv genotyping by PCR-SSP [PDF]

Journal of Thrombosis and Haemostasis, 2003
V, Jallu, C, Kaplan
openaire   +2 more sources

Post-Transfusion Purpura: A Clinical Case With Alveolar Haemorrhage. [PDF]

Respirol Case Rep
Yamakova Y, Pisanchev A, Farfarov A, Petkov R.   +3 more
europepmc   +1 more source