Results 71 to 80 of about 4,221 (179)
High frequency of JCV DNA detection in prostate cancer tissues [PDF]
, 2015 BACKGROUND: Prostate cancer (PC) represents the most frequently diagnosed cancer in men. Exposure to infectious agents has been considered to induce prostatic inflammation and cancerous transformation.
Anzivino, Elena +7 more
core
The Role of Subcellular Distribution upon Signalling by Polyomavirus Middle Tumour-antigen [PDF]
, 2014 The middle T-antigen (MT) encoded by polyomavirus induces tumours by mimicking an activated cell surface receptor. A hydrophobic region close to the C-terminus locates MT to the plasma membrane where it initiates oncogenic signalling.
Zhou, Yunsi
core +1 more source
The Role of APOBEC3B in Cancer: Mechanisms, Clinical Challenges, and Therapeutic Opportunities
Human Mutation, Volume 2026, Issue 1, 2026.Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like 3B (APOBEC3B, A3B) is a key cytidine deaminase that induces genomic instability and clonal evolution in diverse malignancies. Although A3B plays a key role in the onset and advancement of various cancers, a comprehensive model bridging its multifaceted mechanisms and clinical translation ...
Fengfeng Zhou +3 more
wiley +1 more source
Recent advances in conditional cell immortalization technology [PDF]
, 2016 Gene-modified cell therapies are transforming medicine. Over the last 18 months, notable clinical successes using antigen-targeting cellular immunotherapies have been achieved.
Jat, PS, Toledo, GS, Wall, IB
core +1 more source
Advanced Science, Volume 12, Issue 46, December 11, 2025.Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang +19 more
wiley +1 more source
Mouse Polyomavirus T Antigens: Directors of Cell Cycle Signaling [PDF]
, 2015 Polyomaviruses (PyV) efficiently replicate by disrupting host cell signaling pathways. Disruption of the cell cycle is implicated in nearly all tumor formation. Studies of cellular transformation by primate PyV, SV40, and mouse polyomavirus (MPyV) have
Nicholas, Catherine
core +2 more sources
Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges
Head &Neck, Volume 47, Issue 12, Page 3414-3428, December 2025.ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley +6 more
wiley +1 more source
Studies on early cellular responses during Epstein-Barr virus infection [PDF]
, 2015 The human gamma-herpesvirus Epstein-Barr virus (EBV) has been implicated in the pathogenesis of a broad spectrum of lymphoid and epithelial cell malignancies.
Chen, Xinsong
core +1 more source
JEADV Clinical Practice, Volume 4, Issue 5, Page 1101-1113, December 2025.Cutaneous squamous cell carcinoma (cSCC) exhibits a pro‐tumorigenic immune environment, increased oncologic signalling, and tumour remodelling, with three immune subgroups from ‘cold’ to ‘hot’. Organ transplant recipients (OTR) with cSCC showed reduced T‐cells and greater viral enrichment, especially HPV, and a higher disease burden.
Choon Chiat Oh +8 more
wiley +1 more source
Studies on the influence of human papillomaviruses (HPV) and other biomarkers on the prevalence of oropharyngeal cancer and clinical outcome [PDF]
, 2013 Background. Oropharyngeal squamous cell carcinoma (OSCC), where tonsillar (TSCC) and base of tongue squamous cell carcinoma (BOTSCC) dominate, is increasing and is now the most common head and neck squamous cell carcinoma (HNSCC) in Sweden.
Näsman, Anders
core +1 more source