Results 21 to 30 of about 339,699 (263)

Trypanosoma cruzi: serum antibody reactivity to the parasite antigens in susceptible and resistant mice

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
The specific antibody responses were compared among susceptible (A/Sn), moderately susceptible (Balb/c) and resistant (C57 BL/lOJ) mice infected with Trypanosoma cruzi (Y strain).
Elizabeth N. De Gaspari   +5 more
doaj   +1 more source

Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. [PDF]

open access: yesPLoS Pathogens, 2010
Candida albicans in the immunocompetent host is a benign member of the human microbiota. Though, when host physiology is disrupted, this commensal-host interaction can degenerate and lead to an opportunistic infection.
A Brian Mochon   +8 more
doaj   +1 more source

A Molecular-Level Account of the Antigenic Hantaviral Surface [PDF]

open access: yesCell Reports, 2016
Hantaviruses, a geographically diverse group of zoonotic pathogens, initiate cell infection through the concerted action of Gn and Gc viral surface glycoproteins. Here, we describe the high-resolution crystal structure of the antigenic ectodomain of Gn from Puumala hantavirus (PUUV), a causative agent of hemorrhagic fever with renal syndrome.
Li, Sai   +8 more
openaire   +9 more sources

Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface

open access: yesMicrobiology Spectrum
Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine capable of protecting adults from pulmonary TB. The bacterial surface is a critical interface that shapes host-pathogen interactions. Several knowledge gaps persist in
Bianca A. Lepe   +5 more
doaj   +1 more source

IMMUNOGENIC PROPERTIES OF CELLULAR AND EXTRACELLULAR PROTEIN-CONTAINING ANTIGENS OF STAPHYLOCOCCUS AUREUS

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. Comparative study of immunobiological properties of cell wall surface antigens and extracellular protein-containing antigens of Staphylococcus aureus. Materials and methods.
I. M. Gruber   +6 more
doaj   +1 more source

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

open access: yesNature Communications, 2020
The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina   +23 more
doaj   +1 more source

Treatment of Schistosoma mansoni with miltefosine in vitro enhances serological recognition of defined worm surface antigens. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of the parasite. The current study examined
Marwa H El-Faham   +6 more
doaj   +1 more source

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

open access: yesMalaria Journal, 2008
Background The insertion of parasite antigens into the host erythrocyte membrane and the structure and distribution of Plasmodium falciparum adhesion receptors on that membrane are poorly understood.
Arnot David E   +7 more
doaj   +1 more source

A Novel Methodology for Detecting Variations in Cell Surface Antigens Using Cell-Tearing by Optical Tweezers

open access: yesBiosensors, 2022
The quantitative analysis of cell surface antigens has attracted increasing attention due to the antigenic variation recognition that can facilitate early diagnoses.
Chih-Lang Lin   +6 more
doaj   +1 more source

Paired Expression Analysis of Tumor Cell Surface Antigens

open access: yesFrontiers in Oncology, 2017
Adoptive immunotherapy with antibody-based therapy or with T cells transduced to express chimeric antigen receptors (CARs) is useful to the extent that the cell surface membrane protein being targeted is not expressed on normal tissues.
Rimas J. Orentas   +7 more
doaj   +1 more source

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