Results 21 to 30 of about 554,352 (307)
Helping tumour antigens to the surface [PDF]
Using high-resolution proteomics to analyse clinical samples from patients with advanced melanoma, Harel et al. show that the metabolic state of melanoma is associated with changes in antigen presentation-related proteins and thereby with response to immunotherapies.
openaire +2 more sources
Detection of microbial surface antigens that bind Lewisa antigen [PDF]
There is evidence that the Lewis(a) blood group antigen is one of the receptors for a number of potentially pathogenic microorganisms. To determine how widely distributed the microbial adhesins are that bind this antigen, anti-idiotypic antibodies produced against monoclonal anti-Lewis(a) were used in coagglutination assays to screen a variety of ...
S. D. Essery+6 more
openaire +3 more sources
Acinetobacter baumannii is an important human pathogen causing substantial mortality in hospitalized patients for which treatment with antibiotics has become problematic due to growing antibiotic resistance.
Maryam Mobarak Qamsari+5 more
doaj +1 more source
Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance [PDF]
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding ...
Dariush Shanehbandi+6 more
doaj +1 more source
MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. [PDF]
Mucosal surfaces regulate defenses against infection and excessive inflammation. We previously showed that human tears upregulated epithelial expression of genes encoding RNase7 and ST2, which inhibited Pseudomonas aeruginosa invasion of human corneal ...
Chan, Gary+5 more
core +2 more sources
A Molecular-Level Account of the Antigenic Hantaviral Surface [PDF]
Hantaviruses, a geographically diverse group of zoonotic pathogens, initiate cell infection through the concerted action of Gn and Gc viral surface glycoproteins. Here, we describe the high-resolution crystal structure of the antigenic ectodomain of Gn from Puumala hantavirus (PUUV), a causative agent of hemorrhagic fever with renal syndrome.
Li, Sai+8 more
openaire +9 more sources
The specific antibody responses were compared among susceptible (A/Sn), moderately susceptible (Balb/c) and resistant (C57 BL/lOJ) mice infected with Trypanosoma cruzi (Y strain).
Elizabeth N. De Gaspari+5 more
doaj +1 more source
Treatment of Schistosoma mansoni with miltefosine in vitro enhances serological recognition of defined worm surface antigens. [PDF]
Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of the parasite. The current study examined
Marwa H El-Faham+6 more
doaj +1 more source
Tuberculosis (TB) is the leading cause of infectious disease death and lacks a vaccine capable of protecting adults from pulmonary TB. The bacterial surface is a critical interface that shapes host-pathogen interactions. Several knowledge gaps persist in
Bianca A. Lepe+5 more
doaj +1 more source
Aim. Comparative study of immunobiological properties of cell wall surface antigens and extracellular protein-containing antigens of Staphylococcus aureus. Materials and methods.
I. M. Gruber+6 more
doaj +1 more source