Results 111 to 120 of about 960,547 (305)
Preclinical Development of Oncolytic Immunovirotherapy for Treatment of HPVPOS Cancers
Molecular Therapy: Oncolytics, 2018 Immunotherapy for HPVPOS malignancies is attractive because well-defined, viral, non-self tumor antigens exist as targets. Several approaches to vaccinate therapeutically against HPV E6 and E7 antigens have been adopted, including viral platforms such as
Lukkana Suksanpaisan +16 more
doaj +1 more source
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
Advanced Healthcare Materials, EarlyView.The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Ode to Oseltamivir and Amantadine?
Canadian Journal of Infectious Diseases and Medical Microbiology, 2006 Influenza A and B viruses are the two major types of influenza viruses that cause human epidemic disease. Influenza A viruses are further categorized into subtypes based on two surface antigens: hemagglutinin (H) and neuraminidase (N).
JM Conly, BL Johnston
doaj +1 more source
Frontiers in Immunology, 2014 Effective viral clearance requires the induction of virus-specific CD8+ cytotoxic T lymphocytes (CTL). Since dendritic cells (DC) have a central role in initiating and shaping virus-specific CTL responses, it is important to understand how DC initiate ...
Nadine eVan Montfoort +2 more
doaj +1 more source
Surface-displayed viral antigens on Salmonella carrier vaccine
, 2000 We have developed a recombinant live oral vaccine using the ice- nucleation protein (Inp) from Pseudomonas syringae to display viral antigens on the surface of Salmonella spp.
Chul Joong Kim +7 more
core +1 more source
Properties of recombinant HIV and SIV antigens [PDF]
, 1992 When expressed in Spodoptera frugiperda cells using recombinant baculoviruses, the HIV - 1 gag gene product, p55, self assembles to form immature HIV core like particles that are secreted into the culture medium.
Jowett, Jeremy Bryan Mark. +1 more
core +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
A tumor-binding antibody with cross-reactivity to viral antigens
Cancer Immunology, ImmunotherapyBackground We previously identified in non-small cell lung cancer (NSCLC) patients an autoantibody to complement factor H (CFH) that is associated with non-metastatic disease and longer time to progression in patients with stage I disease.
Michael J. Campa +3 more
doaj +1 more source