Results 91 to 100 of about 960,547 (305)

Temporal regulation of murine cytomegalovirus transcription and mapping of viral RNA synthesized at immediate early times after infection [PDF]

, 1984
The replication of murine cytomegalovirus strain Smith in murine embryonic fibroblasts was investigated at immediate early, early, and late times after infection.
Koszinowski, Ulrich H., Ebeling-Keil, Angelika, Keil, Günther M.   +2 more
core   +1 more source

Outer membrane vesicles (OMVs) and their therapeutic potential as anti-infectious agents

Nano Trends
Outer membrane vesicles (OMVs) derived from Gram-negative bacteria have emerged as promising therapeutic agents for combating infectious diseases. These small, spherical structures carry diverse cargo molecules, including virulence factors, antigens, and
Mariana Ottaiano Gonçalves, Paula Maria Pincela Lins, Giulia Kassab, Vanderlei Bagnato, Valtencir Zucolotto   +4 more
doaj   +1 more source

Mechanism of viral antigen processing and presentation.

Uirusu, 1993
Zinkernagel & Doherty (1974)によるキラーT細胞のウイルス感染標的細胞認識におけるMHC拘束性の発見から20年足らずで, この問題がウイルス抗原プロセッシングに関するMHC拘束性を反映したものであることが明らかになってきた。この経過も興味あるもので, この間にクラスI及びクラスII経路の違いも明らかになってきた。従来, 熱不活化インフルエンザウイルスを用いて抗原提示機構の独自の研究を続けてきた我々の研究室では, 国産のMHC表現欠損細胞をいただいて, ウイルス抗原提示機構の研究の新しい局面を切り開いている。インフルエンザウイルス-L929細胞 (H-2k) の系で研究を続けてきた経過から, 変異細胞はH-2kマウス由来のものである必要があった。C3Hマウス由来の ...
Hosaka, Yasuhiro, Kuroda, Kazumichi
openaire   +3 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Assessment of Different Newcastle Disease Virus Antigens and Inactivators of Binary Ethylene Amine and Formalin for the Hemagglutination Inhibition Assay [PDF]

Archives of Razi Institute
Background and Objectives: Newcastle disease is a severe viral threat to the global poultry industry due to its high prevalence and rapid transmission.
Fatemeh Rahmanzad, fatemeh Amininajafi, Alireza Bahonar, Kaveh Parvandar Asadollahi   +3 more
doaj   +1 more source

Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]

, 2011
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E., Smith, H., Ji, Minjun, Mike Doenhoff, Emily Dawson, Claire Alexander, Gilis, Henk, van Gool, T., Cara Aitken (135264), Grant Spence, Aitken, Cara, Aitken, C., Bailey, W., Cara Aitken, Minjun Ji (135275), Spence, G., Spence, Grant, Henk Gilis, Tom van Gool, Doenhoff, M., Claire Alex, Wendi Bailey, Mike Doenhoff (135259), Gilis, H., Huw Smith, Doenhoff, Mike, van Gool, Tom, Dawson, Emily, Smith, Huw, Tom van Gool (135295), Henk Gilis (135283), Claire Alexander (20985), Minjun Ji, Bailey, Wendi, Grant Spence (135288), Alexander, C., Ji, M., Huw Smith (135256), Wendi Bailey (135270), Emily Dawson (135279), Alexander, Claire   +40 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Autoradiographic detection of IgG and viral antigens

Journal of Immunological Methods, 1982
Autoradiographic methods can be used as an alternative to indirect immunofluorescence to detect viral antigen expression or the presence of IgG in tissue sections. Iodinated protein A isolated from Staphylococcus aureus detects an influx of IgG into the central nervous system of mice inoculated with the coronavirus SD.
Gerdes, J.C., McNally, I., Hileman, L., Burks, J.S.   +3 more
openaire   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source