Results 161 to 170 of about 214,753 (272)

Validation of new equipment for SARS-CoV-2 diagnosis in Ecuador: Detection of the virus and antibodies generated by disease and vaccines with one POC device. [PDF]

PLoS One
Villota SD, Veloz-Villavicencio E, Garcia-Iturralde S, Arévalo JV, Lu S, Jaenes K, Guo Y, Cicek S, Colwill K, Gingras AC, Bremner R, Ponce P, Pardee K, Cevallos VE.   +13 more
europepmc   +1 more source

ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen, Yuan‐Yuan Wei, Jia‐Ying Kang, Da‐Wei Zhang, Jing‐Jing Ye, Xi‐Shi Sun, Mei Hong, Wen‐Ting Zhang, Hui‐Mei Wu, Zhen‐Xing Ding, Guang‐He Fei   +10 more
wiley   +1 more source

Immunotherapy that leverages HPV-specific immune responses for precancer lesions of cervical cancer

Taiwanese Journal of Obstetrics & Gynecology
Cervical cancer and its precursor lesion, cervical intraepithelial neoplasia (CIN), are caused by high-risk human papillomavirus (HPV) viral infection and are highly susceptible to host immunity targeting of HPV viral proteins, which include both foreign
Osamu Kobayashi, Ayumi Taguchi, Takahiro Nakajima, Yuji Ikeda, Keisuke Saito, Kei Kawana   +5 more
doaj  

The intersection of influenza infection and autoimmunity. [PDF]

Front Immunol
Xie S, Wei J, Wang X.
europepmc   +1 more source

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

Therapeutic mucosal vaccination of herpes simplex virus type 2 infected guinea pigs with an adenovirus-based vaccine expressing the ribonucleotide reductase 2 and glycoprotein D induces local tissue-resident CD4+ and CD8+ TRM cells associated with protection against recurrent genital herpes. [PDF]

Front Immunol
Quadiri A, Prakash S, Vahed H, Tadros JM, Sun M, Hormi-Carver KK, Patel SJ, BenMohamed L.   +7 more
europepmc   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

Viral contamination in cell culture: analyzing the impact of Epstein Barr virus and Ovine Herpesvirus 2. [PDF]

Front Microbiol
Bastawecy IM, Abdelmonem M, Afify AF, Saad N, Shirosaki Y, Abdullah CAC, El Naggar RF, Rohaim MA, Munir M.   +8 more
europepmc   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

Low-temperature enhances production of severe fever with thrombocytopenia syndrome virus virus-like particles. [PDF]

Appl Microbiol Biotechnol
Loop I, Ke YD, Chen WJ, Tsai KH, Hsu WL, Fan YC.   +5 more
europepmc   +1 more source