Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Tumor estromal gastrointestinal
Anales de la Facultad de Medicina, 2010 Los tumores estromales gastrointestinales son los tumores mesenquimáticos más frecuentes. Se localizan con frecuencia en el estómago y sus manifestaciones clínicas son variadas.
Rolando Mendívil +4 more
doaj
Antigenic Relations of Blood Group Antigens as Suggested by Tests with Lectins [PDF]
, 1954 William C. Boyd, Elizabeth Shapleigh
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Realization of features of immune response by dynamical system models and a possible mechanism of memory of antigen invasion [PDF]
arXiv, 2006 Among features of real immune responses which occur when antigens invade a body,there are two remarkable features. One is that the amount of antibodies produced in the secondary invasion by the same antigens is more than 10 times larger than that in the primary invasion. The other is that more effective antibodies which can neutralize the antigens more
arxiv
EVIDENCE FOR EPISTATIC ACTION OF GENES FOR ANTIGENIC SUBSTANCES IN SHEEP [PDF]
, 1954 Jan Rendel +2 more
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Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs [PDF]
, 1989 The nuclear distribution of DNA polymerase alpha and PCNA/cyclin in embryonic nuclei has been investigated, in a cell-free extract of Xenopus eggs that recapitulates a basic cell-cycle in vitro, by indirect immunofluorescence microscopy.
Hutchison, C, Kill, IR
core
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Mathematical modeling of antigenicity for HIV dynamics [PDF]
MathS In Action 3, 1 (2010) 1-35, 2008 This contribution is devoted to a new model of HIV multiplication motivated by the patent of one of the authors. We take into account the antigenic diversity through what we define "antigenicity", whether of the virus or of the adapted lymphocytes. We model the interaction of the immune system and the viral strains by two processes.
arxiv
Studies on the Antigens of Human Red Cells [PDF]
, 1950 Merwin Moskowitz +3 more
openalex +1 more source