Results 151 to 160 of about 2,390,491 (336)

Nanobodies Right in the Middle: Intrabodies as Toolbox to Visualize and Modulate Antigens in the Living Cell [PDF]

, 2020
Teresa R. Wagner, Ulrich Rothbauer
openalex   +1 more source

Immunization with a multi-antigen targeted DNA vaccine eliminates chemoresistant pancreatic cancer by disrupting tumor-stromal cell crosstalk [PDF]

, 2023
Hongquan Qin, Jiali Chen, Katia Bouchekioua‐Bouzaghou, Ya-Ming Meng, Jordi Bach Griera, Xue Jiang, Xiangzhan Kong, Minghui Wang, Qiuping Xu, Ping‐Pui Wong   +9 more
openalex   +1 more source

Alternative tumour-specific antigens

Nature Reviews. Cancer, 2019
Christof C. Smith, Sara R. Selitsky, Shengjie Chai, P. Armistead, B. Vincent, J. Serody   +5 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

The Evolution of Vertebrate Antigen Receptors: A Phylogenetic Approach [PDF]

, 2000
Miriam H. Richards, J. Lee Nelson
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Comparison of Multiple Segmentation Methods for Volumetric Delineation of Primary Prostate Cancer with Prostate-Specific Membrane Antigen–Targeted¹⁸F-DCFPyL PET/CT [PDF]

, 2023
Felicia Wang, Chen Liu, Igor Vidal, Margarita Mana-ay, Andrew F. Voter, Lilja B. Sólnes, Ashley E. Ross, Andrei Gafita, Edward M. Schaeffer, Trinity J. Bivalacqua, Kenneth J. Pienta, Martin G. Pomper, Martin A. Lodge, Daniel Y. Song, Jorge D. Oldan, Mohamad E. Allaf, Angelo M. De Marzo, Sara Sheikhbahaei, Michael A. Gorin, Steven P. Rowe   +19 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus

, 2015
Darrell R. Kapczynski, Motoyuki Esaki, Kristi Moore Dorsey, Haijun Jiang, Mark W. Jackwood, Mauro Pires Moraes, Yannick Gardin   +6 more
openalex   +1 more source