Results 161 to 170 of about 2,349,446 (385)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Protective immunity elicited by recombinant bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine. [PDF]

, 1993
The current vaccine against tuberculosis, Mycobacterium bovis strain bacille Calmette-Guerin (BCG), offers potential advantages as a live, innately immunogenic vaccine vehicle for the expression and delivery of protective recombinant antigens (Stover, C ...
Bansal, GP, Barbour, AG, Burlein, JE, Hanson, MS, Koenig, S, Palaszynski, SR, Sadziene, A, Stover, CK, Young, DB, Young, JF   +9 more
core  

Studies on the Mechanism of Inactivation of Human Complement by Plasmin and by Antigen-Antibody Aggregates [PDF]

, 1955
Irwin H. Lepow, Louis Pillemer, Leona Wurz   +2 more
openalex   +1 more source

Alternative tumour-specific antigens

Nature Reviews. Cancer, 2019
Christof C. Smith, Sara R. Selitsky, Shengjie Chai, P. Armistead, B. Vincent, J. Serody   +5 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Functional and metabolic activity of neutrophils in young cattle sensitized with a non-agglutinogenic strain of Brucella

Ветеринария сегодня
Introduction. Brucellosis remains one of the most common highly dangerous zoonotic infections. Resistance to the pathogenic microorganisms of the genus Brucella depends on the appropriate cell-mediated immunity, which includes the activation of the ...
O. O. Manakova, T. A. Yanchenko, V. S. Vlasenko   +2 more
doaj   +1 more source

Heterophile Antigen in Bacteria [PDF]

, 1926
H. M. Powell
openalex   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Competition of haptens [PDF]

, 1966
Groups of rabbits were injected with either bovine serum albumin, sheep red cell stroma, or keyhole limpet hemocyanin to which 2,4-dinitrophenyl and/or p-azophenyl arsonate groups had been coupled. Groups of animals received either doubly coupled antigen
Amkraut, Alfred A., Campbell, Dan H., Garvey, Justine S.   +2 more
core  

STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM [PDF]

, 1953
Joseph V. Jemski, John A. Flick, Warren R. Stinebring   +2 more
openalex   +1 more source