Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Molecular mimicry between parasites and cancer: a novel approach for developing cancer vaccines and therapeutic antibodies. [PDF]
Eissa MM+5 more
europepmc +1 more source
LOCALIZATION OF ANTIGEN IN TISSUE CELLS [PDF]
Melvin H. Kaplan+2 more
openalex +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
A rare case of food-dependent exercise-induced anaphylaxis caused by potato snacks
A rare case of food-dependent exercise-induced anaphylaxis caused by potato snacks is reported. Specific food triggers for anaphylaxis were identified by using the skin prick test, antigen analysis, and serum IgE assays.
Akiko Ikeda, MD+6 more
doaj
Potential for a Combined Oral Inactivated Whole-Cell Vaccine Against ETEC and <i>Shigella</i>: Preclinical Studies Supporting Feasibility. [PDF]
Terrinoni M+5 more
europepmc +1 more source
PREPARATION AND PROPERTIES OF TYPE-SPECIFIC M ANTIGEN ISOLATED FROM A GROUP A, TYPE 1 HEMOLYTIC STREPTOCOCCUS [PDF]
Rebecca C. Lancefield+1 more
openalex +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse. [PDF]
McArthur HCW+3 more
europepmc +1 more source