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Noncoding regions are the main source of targetable tumor-specific antigens

Science Translational Medicine, 2018
A proteogenomic method identifies potentially actionable tumor-specific antigens and shows that most of them are not coded by classic exons. Expanding the landscape of immunotherapy targets Most searches for druggable tumor-specific antigens (TSAs) start
Céline M. Laumont, K. Vincent, L. Hesnard, E. Audemard, É. Bonneil, J. Laverdure, P. Gendron, M. Courcelles, Marie-Pierre Hardy, C. Côté, C. Durette, Charles St-Pierre, Mohamed Benhammadi, J. Lanoix, S. Vobecky, É. Haddad, S. Lemieux, P. Thibault, C. Perreault   +18 more
semanticscholar   +1 more source