Results 21 to 30 of about 2,037,182 (315)

Identification of protective antigens for vaccination against systemic salmonellosis [PDF]

open access: yes, 2014
There is an urgent medical need for improved vaccines with broad serovar coverage and high efficacy against systemic salmonellosis. Subunit vaccines offer excellent safety profiles but require identification of protective antigens, which remains a ...
Dirk eBumann   +3 more
core   +1 more source

Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology

open access: yesmBio, 2022
Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of antifungal therapies. Currently, there is no vaccine to prevent cryptococcosis.
Jianfeng Lin   +5 more
doaj   +1 more source

Alternative tumour-specific antigens

open access: yesNature Reviews. Cancer, 2019
The study of tumour-specific antigens (TSAs) as targets for antitumour therapies has accelerated within the past decade. The most commonly studied class of TSAs are those derived from non-synonymous single-nucleotide variants (SNVs), or SNV neoantigens ...
Christof C. Smith   +5 more
semanticscholar   +1 more source

Babesia microti Protein BmSP44 Is a Novel Protective Antigen in a Mouse Model of Babesiosis

open access: yesFrontiers in Immunology, 2020
Babesiosis caused by Babesia species imposes an increasing threat to public-health and so far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may participate in the invasion of erythrocytes.
Hui Wang   +6 more
doaj   +1 more source

Structure and genetics of Escherichia coli O antigens

open access: yesFEMS Microbiology Reviews, 2019
Escherichia coli includes clonal groups of both commensal and pathogenic strains, with some of the latter causing serious infectious diseases. O antigen variation is current standard in defining strains for taxonomy and epidemiology, providing the basis ...
Bin Liu   +9 more
semanticscholar   +1 more source

Comparative characteristics of immunohistochemical detection of M. tuberculosis antigens and mycobacteria by Ziehl–Neelsen method in lung tissue with tuberculoma during progressive course of tuberculosis

open access: yesPatologìâ, 2017
The aim of the study – to compare the character of expression of M. tuberculosis antigens in immunohistochemical (IHC) study and detection of acid-fast bacilli (AFB) by Ziehl–Neelsen method in lung tissue with tuberculoma in the chronic course of ...
I. V. Liskina   +4 more
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

open access: yesAnimals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević   +2 more
doaj   +1 more source

Landscape of immunogenic tumor antigens in successful immunotherapy of virally-induced epithelial cancer

open access: yesScience, 2017
Targeting nonviral antigens in viral-driven cancer Adoptive cell transfer harnesses a patient's own T cells to destroy cancer. The strategy can successfully treat epithelial tumors driven by human papillomavirus (HPV), but it remains unclear why only ...
S. Stevanović   +10 more
semanticscholar   +1 more source

Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. [PDF]

open access: yes, 2008
BACKGROUND: The asexual blood stages of the human malaria parasite Plasmodium falciparum produce highly immunogenic polymorphic antigens that are expressed on the surface of the host cell.
Christopher J. Drakeley   +26 more
core   +1 more source

Subunit Vaccine Approaches for African Swine Fever Virus

open access: yesVaccines, 2019
African swine fever virus (ASFV) is the cause of a highly fatal disease in swine, for which there is no available vaccine. The disease is highly contagious and poses a serious threat to the swine industry worldwide. Since its introduction to the Caucasus
Natasha N. Gaudreault   +1 more
doaj   +1 more source

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