Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
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Hybrid cell lines producing monoclonal antibodies directed against Treponema [PDF]
Continuous hybrid cell lines for producing monoclonal antibodies directed against antigens of Treponema pallidum have been developed. The hybrid cell lines were established by fusing differentiated lymphoid cells primed with antigens of Treponema ...
Kettman, John R., Norgard, Michael V.
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Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
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Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen [PDF]
Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens.
Byrne, GW +4 more
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Aspectos estruturais da membrana eritrocitária Structural aspects of the erythrocyte membrane
Este artigo descreve as estruturas e funções da membrana eritrocitária e sua importância na medicina transfusional. A membrana eritrocitária é uma das membranas mais conhecidas em termos de estrutura, função e genética. Como qualquer membrana plasmática,
Priscila Murador, Elenice Deffune
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Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys [PDF]
We transplanted kidneys from α1,3-galactosyltransferase knockout (GalT-KO) pigs into six baboons using two different immunosuppressive regimens, but most of the baboons died from severe acute humoral xenograft rejection. Circulating induced antibodies to
Anthony Jevnikar +33 more
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Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. [PDF]
BACKGROUND: Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are ...
AA Odutola +46 more
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An Update of Bovine Hemoplasmas Based on Phylogenetic and Genomics Analysis
Mycoplasma wenyonii and ‘Candidatus Mycoplasma haemobos’ are bacteria that have been described as significant hemoplasmas that infect cattle worldwide. Currently, three bovine hemoplasma genomes are known.
Diana Laura Flores-García +4 more
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Leucoreduction of blood components. an effective way to increase blood safety? [PDF]
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria +6 more
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Soluble HIV-1 envelope glycoprotein (Env) trimers are under active investigation as vaccine candidates in relevant pre-clinical models. Like SOSIPs, the cleavage-independent native flexibly linked (NFL) trimers are faithful mimics of the Env spike. Here,
Lifei Yang +13 more
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