Results 21 to 30 of about 645,246 (268)

Protocol for T-cell Adhesion Strength on Tumor Cells under Flow Conditions

open access: yesBio-Protocol, 2013
This method allows evaluating the relative adhesion strength between T lymphocytes and specific adherent target cells using a shear force in flow chambers.
Marie Boutet   +3 more
doaj   +1 more source

Discriminating antigen and non-antigen using proteome dissimilarity: bacterial antigens [PDF]

open access: yesBioinformation, 2010
It has been postulated that immunogenicity results from the overall dissimilarity of pathogenic proteins versus the host proteome. We have sought to use this concept to discriminate between antigens and non-antigens of bacterial origin. Sets of 100 known antigenic and nonantigenic peptide sequences from bacteria were compared to human and mouse ...
Ramakrishnan, Kamna, Flower, Darren R
openaire   +3 more sources

Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology

open access: yesmBio, 2022
Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of antifungal therapies. Currently, there is no vaccine to prevent cryptococcosis.
Jianfeng Lin   +5 more
doaj   +1 more source

Babesia microti Protein BmSP44 Is a Novel Protective Antigen in a Mouse Model of Babesiosis

open access: yesFrontiers in Immunology, 2020
Babesiosis caused by Babesia species imposes an increasing threat to public-health and so far, there is no effective vaccine to prevent Babesia infections. Babesia surface antigen may participate in the invasion of erythrocytes.
Hui Wang   +6 more
doaj   +1 more source

Antigen Stability Controls Antigen Presentation [PDF]

open access: yesJournal of Biological Chemistry, 2004
We investigated whether protein stability controls antigen presentation using a four disulfide-containing snake toxin and three derivatives carrying one or two mutations (L1A, L1A/H4Y, and H4Y). These mutations were anticipated to increase (H4Y) or decrease (L1A) the antigen non-covalent stabilizing interactions, H4Y being naturally and frequently ...
Robert, Thai   +6 more
openaire   +2 more sources

Comparative characteristics of immunohistochemical detection of M. tuberculosis antigens and mycobacteria by Ziehl–Neelsen method in lung tissue with tuberculoma during progressive course of tuberculosis

open access: yesPatologìâ, 2017
The aim of the study – to compare the character of expression of M. tuberculosis antigens in immunohistochemical (IHC) study and detection of acid-fast bacilli (AFB) by Ziehl–Neelsen method in lung tissue with tuberculoma in the chronic course of ...
I. V. Liskina   +4 more
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

open access: yesAnimals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević   +2 more
doaj   +1 more source

Antigen Processing of a Short Viral Antigen by Proteasomes [PDF]

open access: yesJournal of Biological Chemistry, 2006
Mass spectrometry (MS)-based methods coupled to reverse phase chromatography separation are a useful technology to analyze complex peptide pools that are comprised of different peptides with unrelated sequences. In antigen presentation, proteasomes generate a set of short peptides that are closely related and overlapping and in some instances may even ...
Lopez, Daniel   +4 more
openaire   +3 more sources

Subunit Vaccine Approaches for African Swine Fever Virus

open access: yesVaccines, 2019
African swine fever virus (ASFV) is the cause of a highly fatal disease in swine, for which there is no available vaccine. The disease is highly contagious and poses a serious threat to the swine industry worldwide. Since its introduction to the Caucasus
Natasha N. Gaudreault   +1 more
doaj   +1 more source

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis

open access: yesVaccines, 2021
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj   +1 more source

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