Results 41 to 50 of about 2,037,182 (315)

Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage

open access: yesFrontiers in Immunology, 2018
Soluble HIV-1 envelope glycoprotein (Env) trimers are under active investigation as vaccine candidates in relevant pre-clinical models. Like SOSIPs, the cleavage-independent native flexibly linked (NFL) trimers are faithful mimics of the Env spike. Here,
Lifei Yang   +13 more
doaj   +1 more source

Immunophenotypic Aberrancies in Acute Leukemia: A Tertiary Care Centre Experience

open access: yesOman Medical Journal, 2021
Objectives: Acute leukemias (AL) are a heterogeneous group of hematological malignancies with the presence of 20% or more blasts in the peripheral blood or bone marrow.
Monika Gupta   +5 more
doaj   +1 more source

Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]

open access: yes, 2010
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO   +7 more
core   +1 more source

Human Vaccines in India: Present and Future Perspectives

open access: yesMGM Journal of Medical Sciences, 2019
Vaccines are formulations that equip the human immune system to fight against a pathogen. All the vaccines approved for use are safe. On vaccination, the body produces enough clonal B and T cells to resist infection.
Prasanta Kumar Ghosh
doaj   +1 more source

Verificación del desempeño de la prueba rápida "AMP Rapid Test SARS-CoV-2 IgG/IgM- Cassettes"

open access: yesInfectio, 2021
Objective: We aimed to realize a verification of the performance of the rapid serological tests used in Risaralda department.Methods: Analytical, cross-sectional study.
Diana María Gil-Villa
doaj   +1 more source

THE BIOTIC FACTOR OF TREMATOD OPISTHORHIS FELINEUS INVASION INFLUENCE ON HOST IMMUNE STATUS AND SOMATIC CELLS PROLIFERATIVE ACTIVITY

open access: yesИнфекция и иммунитет, 2016
The paper confirms long-time opisthorhis invasion role as a risk factor of host immune system reconstitution as well as an important factor in holangiocarcinomas development. It was shown that opisthorhosis invasion primal stage induce host immune system
A. G. Rybka
doaj   +1 more source

DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES

open access: yesJournal of Experimental Medicine, 1965
Two methods were used to demonstrate the presence of tumor-specific antigens in adenocarcinomata of the human colon: (a) rabbits were immunized with extracts of pooled colonic carcinomata, and the antitumor antisera thus produced were absorbed with a ...
P. Gold, S. O. Freedman
semanticscholar   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

open access: yesFrontiers in Immunology, 2018
CD22 (Siglec 2) is a receptor predominantly restricted to B cells. It was initially characterized over 30 years ago and named “CD22” in 1984 at the 2nd International workshop in Boston (1).
Edward A. Clark   +2 more
doaj   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh   +4 more
wiley   +1 more source

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