Results 61 to 70 of about 2,037,182 (315)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Field evaluation of inactivated Corynebacterium ovis vaccine in sheep prepared from a local isolate

Journal of Veterinary Medical Research, 2016
Corynebacterium pseudotuberculosis vaccine was prepared from a local field isolate. Vaccination of sheep with 50g PLD toxoid and 10 mg bacterin adjuvanted with Montanide oil improved the levels of immune responses of sheep.
Nabila A. Ghazy, Mohamed G. Abdelwahab, Makhareta M.A.M., Abdallah Y.A.   +3 more
doaj  

Comprehensive Characterization of Reference Standard Lots of HIV-1 Subtype C Gp120 Proteins for Clinical Trials in Southern African Regions

Vaccines, 2016
Two HIV-1 subtype C gp120 protein candidates were the selected antigens for several experimental vaccine regimens now under evaluation in HVTN 100 Phase I/II clinical trial aiming to support the start of the HVTN 702 Phase IIb/III trial in southern ...
Zihao Wang, Clarisse Lorin, Marguerite Koutsoukos, David Franco, Babak Bayat, Ying Zhang, Andrea Carfi, Susan W. Barnett, Frederick Porter   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Serodiagnosis of Echinococcus spp. infection: explorative selection of diagnostic antigens by peptide microarray [PDF]

, 2010
BACKGROUND: Production of native antigens for serodiagnosis of helminthic infections is laborious and hampered by batch-to-batch variation. For serodiagnosis of echinococcosis, especially cystic disease, most screening tests rely on crude or purified ...
Maag, Eva, List, C, List, C., Gottstein, Bruno, Gottstein Bruno, Felger Ingrid, Felger, Ingrid, Qi, W, Gottstein, B., Ingrid Felger, Maag Eva, Qi Weihong, Müller, N., Felger, I, Müller, Norbert, Norbert Müller, List, Claudia, Gottstein, B, Müller Norbert, Felger, I., Maag, E., Müller, N, Qi, W., Eva Maag, Bruno Gottstein, List Claudia, Claudia List, Maag, E, Qi, Weihong, Weihong Qi, Qi W, List C, Gottstein B, Maag E, Müller N, Felger I   +35 more
core   +2 more sources

Molecular typing of RhD-negative blood donors with C and/or E antigen [PDF]

Scripta Medica, 2019
Background: Most people are either RhD positive or RhD negative, but there is also a number of persons with D antigen variants. The aim of this study was to prove, by using molecular diagnostic tests, whether the RHD gene and D antigen on the red cell ...
Guzijan Gordana, Milosavić Milanka, Radojković-Sredić Danijela, Lilić Marko, Jukić Biljana   +4 more
doaj  

Identificación de antígenos de aislamientos colombianos de Giardia duodenalis reconocidos por IgG total y subclases.

Biomédica: revista del Instituto Nacional de Salud, 2003
Se conocen investigaciones realizadas sobre la respuesta inmune humoral en giardiosis. Sin embargo, estudios sobre perfiles de antígenos de quistes y de trofozoítos de Giardia duodenalis reconocidos por IgG y subclases (IgG1, IgG2, IgG3, IgG4) anti-G ...
Jenny Fabiola Hernández, Sofía Duque, Adriana Arévalo, Rafael Guerrero, Rubén Santiago Nicholls   +4 more
doaj   +1 more source

Mining Exomic Sequencing Data to Identify Mutated Antigens Recognized by Adoptively Transferred Tumor-reactive T cells

Nature Medicine, 2013
Substantial regressions of metastatic lesions have been observed in up to 70% of patients with melanoma who received adoptively transferred autologous tumor-infiltrating lymphocytes (TILs) in phase 2 clinical trials.
P. Robbins, Yong-Chen Lu, M. El-Gamil, Yong F. Li, Colin Gross, Jared J. Gartner, Jimmy Lin, J. Teer, Paul F. Cliften, Eric Tycksen, Yardena Samuels, S. Rosenberg   +11 more
semanticscholar   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modification of H-2 Antigenic Sites by Enzymatic Treatment Influences Virus-Specific Target Cell Lysis [PDF]

, 1976
Vaccinia virus-infected cells were treated enzymatically to remove H-2 antigenic sites. The effect of this procedure on virus-specific cell-mediated cytolysis (CMC) and virus-specific antibody-mediated cytolysis (AMC) was tested. Due to the inhibition of
Koszinowski, Ulrich H., Ertl, H.
core   +1 more source