Results 71 to 80 of about 2,037,182 (315)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Characterization of vaccine antigens of meningococcal serogroup W isolates from Ghana and Burkina Faso from 2003 to 2009 [PDF]
, 2014 Neisseria meningitidis is a major cause of bacterial meningitis and a considerable health problem in the 25 countries of the 'African Meningitis Belt' that extends from Senegal in West Africa to Ethiopia in the East.
Calman MacLennan +17 more
core +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2003 Se conoce poco acerca del papel de la IgA en la respuesta inmune de la giardiosis. El propósito de este trabajo fue identificar los antígenos estimuladores de la producción de IgA anti-Giardia duodenalis de aislamientos colombianos del parásito.
Rosana Natalia Olmos +6 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
ANALYSIS OF IMMUNODOMINANT ANTIGENS OF PORPHYROMONAS GINGIVALIS 381 IN HIGH RESPONDER PATIENTS [PDF]
, 1993 The purpose of this study was to determine the immunodominant antigens of P. gingivalis 381 and to examine their composition and molecular weight. Fourteen periodontal patients, with high antibody titers to P.
Elizabeth, A. BOUTSI
core +1 more source
Nanoparticle Vaccines Against Infectious Diseases
Frontiers in Immunology, 2018 Due to emergence of new variants of pathogenic micro-organisms the treatment and immunization of infectious diseases have become a great challenge in the past few years.
Rashmirekha Pati +5 more
doaj +1 more source
Annals of Clinical Microbiology, 2022 Background: We evaluated the diagnostic performance of the Exdia COVID-19 antigen test (Exdia Ag; Precision Biosensor Inc., Korea) as a point-of-care (POC) test performed in the emergency department (ED) for the rapid detection of severe acute ...
In Young Yoo +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Modulation of the Bovine Delayed-Type Hypersensitivity Responses to Defined Mycobacterial Antigens by a Synthetic Bacterial Lipopeptide [PDF]
, 2003 The use of defined protein and peptide antigens can overcome specificity limitations of purified protein derivatives in the detection of bovine tuberculosis when the antigens are used in blood-based tests. Since the use of these specific antigens as skin
Howard, CJ +5 more
core
Non-precipitating protein antigens
, 1941 When some protein antigens are heated with serologically unspecific proteins they cease to be precipitated by their antisera, and their behaviour in vitro approximates to that of non–precipitating haptens.
Bawden, F. C. +3 more
core +1 more source