Results 81 to 90 of about 833,120 (315)

On-Field Evaluation of Exdia COVID-19 Antigen Point-of-Care Testing in the Emergency Department During the COVID-19 Pandemic

Annals of Clinical Microbiology, 2022
Background: We evaluated the diagnostic performance of the Exdia COVID-19 antigen test (Exdia Ag; Precision Biosensor Inc., Korea) as a point-of-care (POC) test performed in the emergency department (ED) for the rapid detection of severe acute ...
In Young Yoo, Gun Dong Lee, Hyojin Chae, Chun Song Youn, Eun-Jee Oh, Yeon-Joon Park   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Non-precipitating protein antigens

, 1941
When some protein antigens are heated with serologically unspecific proteins they cease to be precipitated by their antisera, and their behaviour in vitro approximates to that of non–precipitating haptens.
Bawden, F. C., Kleczkowski, A.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Tumor associated antigens in diagnosis of serous effusions [PDF]

, 1988
The use of tumour associated antigens in the diagnosis of serous effusions was studied in 76 patients with benign and 200 patients with malignant disease.
Permanetter, W., Mezger, J., Lamerz, Rolf, Wilmanns, W., Gerbes, Alexander L.   +4 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial. [PDF]

, 2009
BACKGROUND: Praziquantel treatment of schistosomiasis during pregnancy was only recommended in 2002; hence the effects of treatment during pregnancy are not fully known. We have therefore evaluated the effects on infection intensity and the immunological
Emojong Nicholas O, Dunne, David W., Mawa, Patrice A, Birgitte J Vennervald, Jones Frances M, Jones, Frances M., Duong, Trinh, Patrice A Mawa, Emojong, Nicholas O., Vennervald, Birgitte J, Mawa Patrice A, Frances M Jones, Alison M Elliott, Trinh Duong, Mpairwe Harriet, Elliott, Alison M, Robert Tweyongyere, Mawa, Patrice A., Mpairwe, Harriet, Emojong, Nicholas O, Dunne, David W, Katunguka-Rwakishaya Eli, Elliott Alison M, Tweyongyere, Robert, David W Dunne, Katunguka-Rwakishaya, Eli, Dunne David W, Elliott, Alison M., Duong Trinh, Vennervald Birgitte J, Nicholas O Emojong, Eli Katunguka-Rwakishaya, Tweyongyere Robert, Jones, Frances M, Harriet Mpairwe   +34 more
core   +1 more source

Main features of DNA-based immunization vectors

Brazilian Journal of Medical and Biological Research, 1999
DNA-based immunization has initiated a new era of vaccine research. One of the main goals of gene vaccine development is the control of the levels of expression in vivo for efficient immunization.
V. Azevedo, G. Levitus, A. Miyoshi, A.L. Cândido, A.M. Goes, S.C. Oliveira   +5 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Analysis of lipopolysaccharide antigens of Treponema hyodysenteriae [PDF]

, 1989
Lipopolysaccharide (LPS) extracts obtained from Treponema hyodysenteriae of serogroups A, B, D and E, and from T. innocens were examined by SDS-polyacrylamide gel electrophoresis (SDS-PAGE), silver-staining, and immunoblotting with hyperimmune rabbit ...
Combs, B., Hampson, D.J., Mhoma, J.R.L.
core