Results 31 to 40 of about 833,120 (315)

Discriminating antigen and non-antigen using proteome dissimilarity: bacterial antigens [PDF]

Bioinformation, 2010
It has been postulated that immunogenicity results from the overall dissimilarity of pathogenic proteins versus the host proteome. We have sought to use this concept to discriminate between antigens and non-antigens of bacterial origin. Sets of 100 known antigenic and nonantigenic peptide sequences from bacteria were compared to human and mouse ...
Ramakrishnan, Kamna, Flower, Darren R
openaire   +3 more sources

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. [PDF]

, 2013
BACKGROUND: Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are ...
Kaufmann, S.H.E., Ambrose, Lyn R., Gomez, M., Martin Ota (198869), Lalor, M., Donkor Simon, Novel N Chegou, Kees Franken, Willem Hanekom (23103), Gerhard Walzl (149313), Mihret, A., Crampin, Amelia C, Simon Donkor (343534), Parida, S., Thiel Bonnie A., Hazel M Dockrell, Hanekom, Willem, GCGH Biomarkers for TB consortium, Amelia C Crampin, Parida, Shreemanta K., Kassa, Desta, Loxton, Andre G., Gomez, M.P., Martin Ota, Crampin, Amelia C., Loxton, Andre G, Rawleigh Howe (456745), Hanekom Willem, Parida Shreemanta K., W. Henry Boom (125099), Simon Donkor, Lalor, Maeve K., Ambrose, Lyn R, Andre G. Loxton (160294), Howe Rawleigh, Dockrell Hazel M., Kassa Desta, Gomez, Marie P., Boom, W. Henry, Sutherland, Jayne S, Franken Kees, Ota, Martin, Stefan H E Kaufmann, GCGH Biomarkers TB Consortium, Stefan H. E. Kaufmann (149315), Walzl, G., Crampin, A.C., Mayanja-Kizza Harriet, Sutherland, Jayne S., Michel R. Klein (160302), Lalor Maeve K., Black, Gillian F, Chegou Novel N., Black, G., Harriet Mayanja-Kizza (78637), Donkor, S., Maeve K Lalor, Gomez Marie P., Boom, W.H., Donkor, Simon, Kassa, D., Loxton, A.G., Kees Franken (456747), Amelia C. Crampin (239427), Ambrose, L.R., Desta Kassa (456743), Crampin, A., Black, Gillian F., Thiel, Bonnie A., Ambrose Lyn R., Dockrell, Hazel M., Lyn R Ambrose, Adane Mihret, Hazel M. Dockrell (255469), Klein Michel R., Parida, Shreemanta K, Franken, K., Dockrell, H.M., Walzl Gerhard, Kaufmann, Stefan H.E., Boom, W Henry, Shreemanta K. Parida (149299), Klein, Michel R., Chegou, Novel N, Klein, M.R., Bonnie A Thiel, Lyn R. Ambrose (456742), Ota Martin, Thiel, B.A., Andre G Loxton, Sutherland, J., Shreemanta K Parida, Harriet Mayanja-Kizza, Ottenhoff Tom H. M., Ota, M., Loxton, A., Howe, R., Mayanja-Kizza, H., Ottenhoff, Tom HM, Tom H M Ottenhoff, Cardona, Pere-Joan, Ottenhoff, T.H.M., Willem Hanekom, Crampin Amelia C., Gomez, Marie P, Novel N. Chegou (160288), Chegou, Novel N., Klein, M., Sutherland, J.S., Lalor, M.K., Thiel, Bonnie A, Bonnie A. Thiel (456748), Maeve K. Lalor (356874), Ottenhoff, T., Walzl, Gerhard, Gillian F. Black (149301), Boom W. Henry, Ambrose, L., Hanekom, W., Marie P Gomez, Lalor, Maeve K, Adane Mihret (456744), Chegou, N.N., Marie P. Gomez (456746), Jayne S Sutherland, Sutherland Jayne S., Klein, Michel R, Chegou, N., Jayne S. Sutherland (334202), Kaufmann, Stefan HE, Parida, S.K., Mihret Adane, Kaufmann Stefan H. E., Ottenhoff, Tom H.M., W Henry Boom, Rawleigh Howe, Thiel, B., Gerhard Walzl, Tom H. M. Ottenhoff (160303), Gillian F Black, Dockrell, H., Black Gillian F., Howe, Rawleigh, Boom, W., Black, G.F., Loxton Andre G., Desta Kassa, Ottenhoff, Tom H M, Kaufmann, S., Mihret, Adane, Franken, Kees, Mayanja-Kizza, Harriet, Michel R Klein, Kaufmann, Stefan H E, Dockrell, Hazel M   +154 more
core   +3 more sources

Comparative characteristics of immunohistochemical detection of M. tuberculosis antigens and mycobacteria by Ziehl–Neelsen method in lung tissue with tuberculoma during progressive course of tuberculosis

Patologìâ, 2017
The aim of the study – to compare the character of expression of M. tuberculosis antigens in immunohistochemical (IHC) study and detection of acid-fast bacilli (AFB) by Ziehl–Neelsen method in lung tissue with tuberculoma in the chronic course of ...
I. V. Liskina, O. A. Melnik, L. M. Zahaba, S. D. Kuzovkova, V. V. Kuts   +4 more
doaj   +1 more source

Enterocytes in Food Hypersensitivity Reactions

Animals, 2021
Food hypersensitivity reactions are adverse reactions to harmless dietary substances, whose causes are hidden within derangements of the complex immune machinery of humans and mammals.
Maja Krstić Ristivojević, Danijela Apostolović, Katarina Smiljanić   +2 more
doaj   +1 more source

Serodiagnosis of Echinococcus spp. infection: explorative selection of diagnostic antigens by peptide microarray [PDF]

, 2010
BACKGROUND: Production of native antigens for serodiagnosis of helminthic infections is laborious and hampered by batch-to-batch variation. For serodiagnosis of echinococcosis, especially cystic disease, most screening tests rely on crude or purified ...
Maag, Eva, List, C, List, C., Gottstein, Bruno, Gottstein Bruno, Felger Ingrid, Felger, Ingrid, Qi, W, Gottstein, B., Ingrid Felger, Maag Eva, Qi Weihong, Müller, N., Felger, I, Müller, Norbert, Norbert Müller, List, Claudia, Gottstein, B, Müller Norbert, Felger, I., Maag, E., Müller, N, Qi, W., Eva Maag, Bruno Gottstein, List Claudia, Claudia List, Maag, E, Qi, Weihong, Weihong Qi   +29 more
core   +2 more sources

Subunit Vaccine Approaches for African Swine Fever Virus

Vaccines, 2019
African swine fever virus (ASFV) is the cause of a highly fatal disease in swine, for which there is no available vaccine. The disease is highly contagious and poses a serious threat to the swine industry worldwide. Since its introduction to the Caucasus
Natasha N. Gaudreault, Juergen A. Richt   +1 more
doaj   +1 more source

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis

Vaccines, 2021
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj   +1 more source

Antigen Stability Controls Antigen Presentation [PDF]

Journal of Biological Chemistry, 2004
We investigated whether protein stability controls antigen presentation using a four disulfide-containing snake toxin and three derivatives carrying one or two mutations (L1A, L1A/H4Y, and H4Y). These mutations were anticipated to increase (H4Y) or decrease (L1A) the antigen non-covalent stabilizing interactions, H4Y being naturally and frequently ...
Robert, Thai, Gervaise, Moine, Michel, Desmadril, Denis, Servent, Jean-Luc, Tarride, André, Ménez, Michel, Léonetti   +6 more
openaire   +2 more sources

Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]

, 2010
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO, D. J. C. MILES, Conway, DJ, N. O. DUAH, Whittle, HC, H. C. WHITTLE, D. J. CONWAY, Miles, DJC   +7 more
core   +1 more source

Humoral immune responses in mice immunized with region of difference DNA vaccine constructs of pUMVC6 and pUMVC7

International Journal of Mycobacteriology, 2017
Background: We aimed to study the antigen-specific antibody responses in mice immunized with recombinant DNA vaccines constructs of pUMVC6 and pUMVC7, containing RD1 and RD9 genes of Mycobacterium tuberculosis.
Shumaila N. M. Hanif, A S Mustafa
doaj   +1 more source