Results 61 to 70 of about 74,021 (384)
Navigating adverse immunostimulation: A practical guide for clinical researchers
British Journal of Clinical Pharmacology, EarlyView.Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort +3 more
wiley +1 more source
Allergology International, 2010 Background: The impairment that pruritic skin diseases have on patient productivity at work, in the classroom, and in daily activities is substantial and needs to be characterized.
Hiroyuki Murota +9 more
doaj +1 more source
Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]
, 2019 Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core +1 more source
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. [PDF]
, 1994 Eosinophil accumulation is a prominent feature of allergic inflammatory reactions, such as those occurring in the lung of the allergic asthmatic, but the endogenous chemoattractants involved have not been identified.
Collins, PD +8 more
core +1 more source
Bilastine: new insight into antihistamine treatment
Clinical and Molecular Allergy, 2015 Bilastine is a new second generation H1-antihistamine recently approved for the symptomatic treatment of allergic rhinitis (AR) and chronic urticaria (CU).
E. Ridolo +4 more
semanticscholar +1 more source
Drug poisonings following bariatric surgery: Case series report
British Journal of Clinical Pharmacology, EarlyView.Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari +3 more
wiley +1 more source
Frontiers in Endocrinology, 2018 Vertebrate eyes are known to contain circadian clocks, but their regulatory mechanisms remain largely unknown. To address this, we used a cell line from human retinal pigment epithelium (hRPE-YC) with stable coexpression of reporters for molecular clock ...
Eri Morioka +4 more
doaj +1 more source
Topical analgesia for acute otitis media [PDF]
, 2006 BACKGROUND: Acute otitis media (AOM) is a spontaneously remitting disease for which pain is the most distressing symptom. Antibiotics are now known to have less benefit than previously assumed.OBJECTIVES: To assess the effectiveness of topical analgesia ...
Del Mar, C +4 more
core +1 more source
The effect of an antihistamine agent on the gastric secretion induced by sinomenine and irgapyrin [PDF]
, 1956 1. Sinomenine and Irgapyrin, the two antirheumatics known to be capable of releasing histamine, caused a marked gastric secretion in the unanesthetized dog. 2.
Bell, M. G. H., Hu, J., Kaparias, I.
core +2 more sources
Bilastine: A novel antihistamine
, 2018 Bilastine is a new second generation H1-antihistamine approved for the symptomatic treatment of allergic rhinitis (AR) and chronic urticaria (CU) in patients older than 12 years of age.
J. Gandhi, K. Godse, Gauri Godse
semanticscholar +1 more source