Results 41 to 50 of about 65,144 (350)
Therapeutic utility of glucocorticoids and antihistamines cotreatment. Rationale and perspectives
Antihistamines and glucocorticoids (GCs) are often used together in the clinic, in several inflammatory‐related situations. Even though there is no clear rationale for this drug association, the clinical practice is based on the assumption that due to ...
Carlos D. Zappia, Federico Monczor
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Background: Motion sickness is a common phenomenon that affects almost everybody at some point in their lifetime. Clinicians should be familiar with the proper management of this condition.
Alexander KC Leung, Kam Lun Hon
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Pharmacotherapy of allergic rhinitis
The clinical picture of allergic rhinitis includes sneezing, nasal discharge, impaired nasal breathing, and itching of the nose and roof of mouth. Depending on the duration of symptoms, allergic rhinitis is divided into intermittent and persistent forms,
V. T. Pal’chun+3 more
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Allergic diseases and pregnancy
Allergic reactions are quite common in pregnant women. The most common manifestations of an allergic reaction during pregnancy are: from the respiratory tract – allergic rhinitis and bronchial asthma, from the skin and subcutaneous tissue ...
A. V. Klemenov
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New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr.+2 more
wiley +1 more source
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
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Molecular mechanism of antihistamines recognition and regulation of the histamine H1 receptor
Histamine receptors are a group of G protein-coupled receptors (GPCRs) that play important roles in various physiological and pathophysiological conditions.
Dandan Wang+7 more
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Histamine and its receptors (H1R–H4R) play a crucial and significant role in the development of various allergic diseases. Mast cells are multifunctional bone marrow-derived tissue-dwelling cells that are the major producer of histamine in the body.
Elden Berla Thangam+8 more
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Rhinitis in general practice [PDF]
A 3 year old boy presented with a 3 week history of nasal obstruction, clear rhinorrhea, difficulty with feeding and a productive cough. Child was afebrile, had occasional watery itchy eyes and mother claimed that at night he tended to wake up a couple ...
drkvassallo@yahoo.co.uk+1 more
core
Quantitative Analysis of Fluorescent Sensor Arrays
Fluorescent sensor arrays have great potential for the quantification of analytes in complex systems. Herein, statistical multivariate techniques and deep learning models to provide quantitative information from such arrays are reviewed. Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to ...
Karandeep Grover+3 more
wiley +1 more source