Results 51 to 60 of about 9,174 (251)

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

British Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen, Ngoc Hoang Le, Nhu Quynh Phan, Toan Trung Duong, Le Thi Anh Thu, Hsuan‐Chia Yang, Chih‐Wei Huang, Min‐Huei Hsu, Jason C. Hsu, Chien‐Tien Su, Phung‐Anh Nguyen   +10 more
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

Flavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang, Wei Meng, Renzhong Wang, Huijun Du   +3 more
wiley   +1 more source

Effects of second generation antihistamines on daily driving with and without subtasks measured in a driving simulator

Discover Applied Sciences
Background Second-generation antihistamines are widely used for the management of allergic conditions. In addition, many second-generation antihistamines are readily available over the counter at pharmacies.
Akihito Nagahama, Atsunobu Sagara, Hayato Aki, Hiroki Yoshimura, Makoto Hiraide, Takatsune Shimizu, Motohiko Sano, Tetsuro Yumoto, Tomoo Hosoe, Kenji Tanaka   +9 more
doaj   +1 more source

Use of second-generation antihistamines in combination treatment of ENT diseases

Медицинский совет, 2015
Currently, allergic diseases are very widespread, and their incidence is increasing at an alarming pace worldwide. [1] According to different authors, from 20 to 50% of the population in European countries suffer from allergic diseases.
A. I. Kryukov, N. L. Kunelskaya, G.Y. T Tsarapkin, G. N. Izotova, S. G. Arzamazov, A. S. Tovmasyan   +5 more
doaj   +1 more source

Primary Non-Adherence to Antihistamines—Conclusions From E-Prescription Pilot Data in Poland

Frontiers in Pharmacology, 2020
BackgroundIn allergic conditions such as allergic rhinitis and urticaria, orally administered H1-antihistamines belong to first-line therapy and therefore, are widely prescribed.
Grzegorz Kardas, Michał Panek, Piotr Kuna, Janusz Cieszyński, Przemysław Kardas   +4 more
doaj   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Efficacy of Combined Oral Isotretinoin and Desloratadine or Levocetirizine vs. Isotretinoin Monotherapy in Treating Acne Vulgaris: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Biomedicines
Background/Objectives: Acne vulgaris is a widespread, chronic inflammatory skin condition that significantly impacts patients’ quality of life.
Julia Woźna, Andrzej Bałoniak, Jan Stępka, Adriana Polańska, Ewa Mojs, Ryszard Żaba   +5 more
doaj   +1 more source

ANALYSIS OF CURRENT THERAPEUTIC APPROACHES TO CHRONIC RHINITIS ACCORDING TO THE POLYCLINIC DATA OF AMBULATORY SERVICE OF MOSCOW

Медицинский совет, 2017
The term «rhinitis» comprises a large heterogeneous group of diseases with different etiology and pathophysiological mechanisms. The latest consensual documents recommend that all rhinitis be classified into 3 main types: infectious, allergic (AR) and ...
E. L. Savlevich, V. S. Kozlov, M. A. Zharkikh, D. A. Chernyshova, E. A. Ruzakova   +4 more
doaj   +1 more source

Comparative analysis of the consumption of antihistamines for systemic use in the Republic of Serbia and Nordic countries in the period 2009-2019 [PDF]

Hospital Pharmacology, 2023
Introduction: According to the ATC system of drug classification, group R06 includes H1 antihistamines for systemic use, which are divided into drug groups of the 1st and 2nd generation. Aim: Since there are no national guidelines in Serbia, for treating
Vuković Milana M., Vesković Dunja M., Todorović Nemanja B., Roš Tatjana N., Jovanović-Ljubičić Jasmina M., Kuzman Danilo D., Lalić-Popović Mladena N., Miljković Dejan M., Milijašević Boris Ž.   +8 more
doaj