Results 41 to 50 of about 37,241 (266)

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Effects of second generation antihistamines on daily driving with and without subtasks measured in a driving simulator

Discover Applied Sciences
Background Second-generation antihistamines are widely used for the management of allergic conditions. In addition, many second-generation antihistamines are readily available over the counter at pharmacies.
Akihito Nagahama, Atsunobu Sagara, Hayato Aki, Hiroki Yoshimura, Makoto Hiraide, Takatsune Shimizu, Motohiko Sano, Tetsuro Yumoto, Tomoo Hosoe, Kenji Tanaka   +9 more
doaj   +1 more source

Efficacy of Combined Oral Isotretinoin and Desloratadine or Levocetirizine vs. Isotretinoin Monotherapy in Treating Acne Vulgaris: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Biomedicines
Background/Objectives: Acne vulgaris is a widespread, chronic inflammatory skin condition that significantly impacts patients’ quality of life.
Julia Woźna, Andrzej Bałoniak, Jan Stępka, Adriana Polańska, Ewa Mojs, Ryszard Żaba   +5 more
doaj   +1 more source

ANALYSIS OF CURRENT THERAPEUTIC APPROACHES TO CHRONIC RHINITIS ACCORDING TO THE POLYCLINIC DATA OF AMBULATORY SERVICE OF MOSCOW

Медицинский совет, 2017
The term «rhinitis» comprises a large heterogeneous group of diseases with different etiology and pathophysiological mechanisms. The latest consensual documents recommend that all rhinitis be classified into 3 main types: infectious, allergic (AR) and ...
E. L. Savlevich, V. S. Kozlov, M. A. Zharkikh, D. A. Chernyshova, E. A. Ruzakova   +4 more
doaj   +1 more source

Comparative analysis of the consumption of antihistamines for systemic use in the Republic of Serbia and Nordic countries in the period 2009-2019 [PDF]

Hospital Pharmacology, 2023
Introduction: According to the ATC system of drug classification, group R06 includes H1 antihistamines for systemic use, which are divided into drug groups of the 1st and 2nd generation. Aim: Since there are no national guidelines in Serbia, for treating
Vuković Milana M., Vesković Dunja M., Todorović Nemanja B., Roš Tatjana N., Jovanović-Ljubičić Jasmina M., Kuzman Danilo D., Lalić-Popović Mladena N., Miljković Dejan M., Milijašević Boris Ž.   +8 more
doaj  

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

ANTIHISTAMINES IN TREATMENT OF CHRONIC URTICARIA. REVIEW OF MODERN RECOMMENDATIONS

Медицинский совет, 2016
The article provides current scientific data on the pathogenesis and symptoms of chronic urticaria; international recommendations for treatment and place of antihistamine drugs; clinical pharmacology of the new antihistamines of the 2nd and 3rd ...
M. V. LEONOVA, A. S. DVORNIKOV, P. A. SKRIPKINA, O. V. MINKINA, T. A. GAIDINA   +4 more
doaj   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Antihistamine therapy in pediatric practice

Медицинский совет, 2018
The article considers the role of histamine in the pathogenesis of allergic diseases and other pathological conditions. The mechanisms that contribute to the development of skin itching are considered separately.
S. V. Tsarev
doaj   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source