Results 61 to 70 of about 44,402 (291)

ANTIHISTAMINES IN TREATMENT OF CHRONIC URTICARIA. REVIEW OF MODERN RECOMMENDATIONS

Медицинский совет, 2016
The article provides current scientific data on the pathogenesis and symptoms of chronic urticaria; international recommendations for treatment and place of antihistamine drugs; clinical pharmacology of the new antihistamines of the 2nd and 3rd ...
M. V. LEONOVA, A. S. DVORNIKOV, P. A. SKRIPKINA, O. V. MINKINA, T. A. GAIDINA   +4 more
doaj   +1 more source

Exercise affects systemic basophil responses in humans: Applying an automated and modified basophil activation test (mBAT) in a field study

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Basophils are effector cells in type I hypersensitivity reactions. Upon cross‐linking of surface‐bound (allergen‐specific) IgE, basophils release a variety of mediators. Determining the activation of basophils ex vivo with anti‐IgE (a basophil activation test or BAT) can be achieved using flow cytometry.
T. C. Pelgrim, B. N. Jukema, L. Koopmans, C. C. W. G. Bongers, M. T. E. Hopman, E. F. Knol, N. Vrisekoop, L. Koenderman   +7 more
wiley   +1 more source

Antihistamine therapy in pediatric practice

Медицинский совет, 2018
The article considers the role of histamine in the pathogenesis of allergic diseases and other pathological conditions. The mechanisms that contribute to the development of skin itching are considered separately.
S. V. Tsarev
doaj   +1 more source

Sex‐specific elevated incidence of glaucoma associated with topiramate versus valproate or lamotrigine in epilepsy, not migraine: A population‐based cohort study

Epilepsia, EarlyView.
Abstract Objective Topiramate has been linked to increased glaucoma risk, potentially through mechanisms involving ocular fluid shifts. However, comparative risks vs other antiseizure medications (ASMs) and variation by sex or indication remain uncertain.
Cuiling Wei, Rachel Yui Ki Chu, Rachel Lancey Lai, Florinda Hui‐Ning Chu, Ian Yu Hin Leung, William Chun Yin Leung, Franco Wing Tak Cheng, Thomas Chi Ho Lam, Ian Chi Kei Wong, Esther Wai Yin Chan, Francisco Tsz Tsun Lai   +10 more
wiley   +1 more source

Allergic rhinitis

Медицинский совет, 2018
Allergic rhinitis is one of the most common disease. The article presents the main aspects of the etiology, pathogenesis, diagnosis and treatment of this nosology.
S. V. Ryazantsev, O. I. Goncharov
doaj   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Antihistamines and Febrile Seizure Susceptibility

Pediatric Neurology Briefs, 2010
Charts of children with febrile seizures admitted to the Hospital of Shiga University of Medical Sciences, Otsu, Japan, 2006-2007, were reviewed retrospectively.
J Gordon Millichap
doaj   +1 more source

Response to Oral Dapsone in a Patient With Generalised Junctional Epidermolysis Bullosa

JEADV Clinical Practice, EarlyView.
ABSTRACT Dapsone is a potent antibacterial agent used as a first‐line treatment for leprosy and employed also as an anti‐inflammatory agent. Additionally, dapsone is used for a variety of other cutaneous conditions. Herein, we report a case of intermediate junctional epidermolysis bullosa that improved significantly with oral 4,4’‐diamino‐diphenyl ...
Shiho Mori, Manabu Fujimoto, Katsuto Tamai   +2 more
wiley   +1 more source