Identifying Promising Immunomodulators for Type 1 Diabetes (T1D) and Islet Transplantation
Type 1 diabetes (T1D) is an autoimmune chronic disorder that damages beta cells in the pancreatic islets of Langerhans and results in hyperglycemia due to the loss of insulin. Exogenous insulin therapy can save lives but does not stop disease progression.
Nida Ajmal +6 more
wiley +1 more source
Infections with cytomegalovirus and other herpesviruses in 121 liver transplant recipients: Transmission by donated organ and the effect of OKT3 antibodies [PDF]
One hundred twenty-one adult liver transplant recipients were studied for the incidence, risk factors, and morbidity associated with herpesviruses infections after transplantation. The overall incidence of infection was 59% for cytomegalovirus (CMV), 35%
Armstrong, JA +7 more
core +1 more source
Use of OKT3 with ciclosporin and steroids for reversal of acute kidney and liver allograft rejection [PDF]
OKT3 monoclonal antibody therapy was added to preexisting baseline immunosuppressive treatment with ciclosporin and steroids to treat rejection in 52 recipients of cadaveric livers and 10 recipients of cadaveric kidneys.
Demetris, AJ, Fung, JJ, Porter, KA
core +1 more source
Percutaneous Nephrostomy for Treatment of Posttransplant Ureteral Obstructions
Introduction: We report our experience with percutaneous management of urologic complications following kidney transplantation.Materials and Methods: Of 1402 consecutive kidney transplant recipients from living donors at our hospital, 21 required ...
Mohammad Hossein Nourbala +3 more
doaj
Induction of specific tolerance by intrathymic injection of recipient muscle cells transfected with donor class I major histocompatibility complex. [PDF]
Induction of tolerance to allogeneic MHC antigens has been a goal in the field of transplantation because it would reduce or eliminate the need for generalized immunosuppression.
Geissler, Edward K. +5 more
core +1 more source
Results of pancreas transplantation after steroid withdrawal under tacrolimus immunosuppression [PDF]
Purpose. The results of steroid withdrawal in pancreas transplant recipients under tacrolimus immunosuppression were analyzed. Methods. From July 4, 1994 until April 30, 1998, 147 pancreas transplantations were performed in 141 patients, including 126 ...
Burke +42 more
core +1 more source
Shwartzman reaction after human renal homotransplantation. [PDF]
In three human recipients, five renal homografts were destroyed within a few minutes to hours after their revascularization in the new host. The kidneys, removed one to 54 days later, had cortical necrosis.
Arhelger +10 more
core +1 more source
Antilymphocyte Serum In Nephrotoxic Serum Nephritis
SummaryALS administration failed to influence the clinical, biochemical, morphological including ultrastructural and immuno-histochemical features of the so-called homolous, and autologous phases of nephrotoxic serum nephritis in rats. This indicates that progression of this form of experimental renal disease is not necessarily dependent upon ...
E R, Fisher, B, Fisher
openaire +2 more sources
Modification of established rejection of canine kidney and liver homografts with antilymphocyte gamma-G globulin [PDF]
Heterologous ALG was administered to ten canine recipients of renal homografts and one recipient of an orthotopic liver. Treatment was started after rejection was well established.
Kashiwagi, N +4 more
core

