Results 171 to 180 of about 113,882 (274)

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Structure-Based Screening of Deep-Sea Microbial Metabolites Against <i>Plasmodium falciparum</i> Dihydroorotate Dehydrogenase. [PDF]

Biology (Basel)
Singh A, Rengasamy KRR, Benjakul S.
europepmc   +1 more source

Organic Nanoparticles in Food Systems as Antimicrobial Agents: Synthesis Strategies, Functional Properties, and Biofilm Inhibition Mechanisms

Nano Select, Volume 7, Issue 4, April 2026.
Organic nanoparticles (ONPs) derived from biopolymers provide sustainable antimicrobial platforms with tunable physicochemical properties. By enabling controlled delivery of bioactive compounds, ONPs disrupt microbial membranes, induce oxidative stress, and inhibit quorum sensing.
Huy Loc Nguyen, Thi Bich Ngoc Nguyen
wiley   +1 more source

Targeted Genomic Surveillance Unveils Genetic Variations Linked to Regional Malaria Drug Resistance Dynamics in India. [PDF]

Open Forum Infect Dis
Khilari A, Sharma S, Bajpai M, Viswan K A, Chaturvedi R, Mirdha BR, Rahi M, Sharma A, Shanmugam D.   +8 more
europepmc   +1 more source

Unveiling the Anticancer Properties of New Synthesized Alkoxy‐ and Methyl Thio‐Chalcone Derivatives

Natural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Breast and cervical cancers are a serious problem and the leading cause of death in women in this decade. Chalcone is a promising compound with great potential for anticancer use. In this work, we synthesized six chalcone derivatives with alkoxy‐ and methylthio‐substituents through Claisen–Schmidt condensation at room temperature.
Nurcahyo Iman Prakoso, Taiki Umezawa, Dwiarso Rubiyanto, Azizah Zelia Kusumo, Fanny Septianingtyas, Muhamad Ikhsan Nurochman, Laras Kristianti, Salmahaminati, Pinus Jumaryatno, Minori Abe   +9 more
wiley   +1 more source

<i>Plasmodium falciparum</i> field isolates drug susceptibility in Mali. [PDF]

JAC Antimicrob Resist
Maiga FO, Dembele L, Dama S, Diakite O, Diallo F, Sogore F, Maiga M, Dao F, Dara N, Alhousseini ML, Traore OB, Djimde AA.   +11 more
europepmc   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, Volume 15, Issue 4, April 2026.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Intelligent <i>in-silico</i> prioritization of antimalarial peptide candidates under explicit physicochemical windows via <i>de novo</i> CTCM-Neo generation and conformal-gated calibrated classification. [PDF]

Front Cell Infect Microbiol
Aamir M, Rezaee K, Anari MS.
europepmc   +1 more source

Efficient One‐Pot Synthesis of Benzothiazole Compounds From Vinamidinium Salts

ChemistryOpen, Volume 15, Issue 4, April 2026.
A catalyst‐free one‐pot reaction of vinamidinium salts with benzothiazole hydrazines efficiently produces 1,3‐bis((3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)propan‐2‐ol (BBTA) and 1‐((1Z,3E)‐1‐(dimethylamino)‐3‐(((Z)‐3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)prop‐1‐en‐2‐yl)pyridin‐1‐ium (DMBT) derivatives.This simple method ...
Zeinab khosravi, Abdolmohammad Mehranpour, Mohammad Reza Mohammadizadeh, Genta Kojya, Satoru Arimitsuc   +4 more
wiley   +1 more source

Targeting <i>Plasmodium falciparum</i> with purine antimetabolites as a therapeutic strategy. [PDF]

Front Microbiol
Tashie W, de Koning HP, Duah-Quashie NO, Quashie NB.   +3 more
europepmc   +1 more source