Results 91 to 100 of about 4,028,312 (182)

World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility-0

, 2011
Copyright information:Taken from "World Antimalarial Resistance Network (WARN) II: In vitro antimalarial drug susceptibility"http://www.biomedcentral.com/1475-2875/6/120Malaria Journal 2007;6():120-120.Published online 6 Sep 2007PMCID:PMC2008206.e of the
Jacques Le Bras (80270), Ronan Jambou (80268), Dennis E Kyle (80273), Pascal Ringwald (80272), Carol Hopkins Sibley (47580), David J Bacon (80267), Thierry Fandeur (80269), Mark M Fukuda (50862), Chansuda Wongsrichanalai (80271)   +8 more
core   +1 more source

Antimalarial Activity of Piperine

Journal of Tropical Medicine, 2018
Malaria remains a public health problem in tropical and subtropical regions. Resistance of Plasmodium falciparum to artemisinins in Southeast Asia is a great concern for disease control and research on discovery and development of new alternative ...
Artitaya Thiengsusuk, Phunuch Muhamad, Wanna Chaijaroenkul, Kesara Na-Bangchang   +3 more
doaj   +1 more source

The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. [PDF]

, 2003
BACKGROUND: The 8-amino and 9-hydroxy substituents of antimalarial cinchona alkaloids have the erythro orientation while their inactive 9-epimers are threo.
Meyer David J, Adagu Ipemida S, Adagu, Ipemida S, Warhurst David C, Sylvia Y Lee, Meyer, David J, David C Warhurst, Craig John C, David J Meyer, Warhurst, David C, Lee, Sylvia Y, Ipemida S Adagu, Craig, John C, John C Craig, Lee Sylvia Y   +14 more
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Diagnostic accuracy of molecular methods for detecting markers of antimalarial drug resistance in clinical samples of Plasmodium falciparum: protocol for an update to a systematic review and meta-analysis

Systematic Reviews, 2018
Background Each year, infection with Plasmodium causes millions of clinical cases of malaria and hundreds of thousands of deaths. Resistance to different antimalarial medications continues to develop and spread, threatening effective prophylaxis and ...
Rebekah Burrow, Thomas R. Fanshawe, Georgina S. Humphreys   +2 more
doaj   +1 more source

Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases? [PDF]

, 2011
Artemisinin-based combination therapy is exerting novel selective pressure upon populations of Plasmodium falciparum across Africa. Levels of resistance to non-artemisinin partner drugs differ among parasite populations, and so the artemisinins are not ...
Mackinnon, Margaret J, COLIN J. SUTHERLAND, MARGARET J. MACKINNON, Babiker, H., MacKinnon, M.J., HAMZA BABIKER, Sutherland, Colin J, Ranford-Cartwright, Lisa, El Sayed, Badria Babiker, Sayed, B.B., Sutherland, C.J., Ranford-Cartwright, L.C., LISA RANFORD-CARTWRIGHT, BADRIA BABIKER EL SAYED, Babiker, Hamza   +14 more
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Resistance to Antimalarial Monotherapy Is Cyclic

, 2022
Malaria is a prevalent parasitic disease that is estimated to kill between one and two million people—mostly children—every year. Here, we query PubMed for malaria drug resistance and plot the yearly citations of 14 common antimalarials ...
Trishna Saha, Ortal Calfon-Peretz, Naamah Bloch, Karin Ben Zaken, Moshe Amitay, Rachel Weitzman, Avi Rosenfeld, Abraham O. Samson   +7 more
core   +1 more source

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis. [PDF]

, 2019
BACKGROUND: Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potentially preclude/pre-empt the detection of subsequent recrudescence of ...
WorldWide Antimalarial Resistance Network Methodology Study Grou
core   +1 more source

PfCRT and its role in antimalarial drug resistance

, 2016
Plasmodium falciparum resistance to chloroquine, the former gold standard antimalarial drug, is mediated primarily by mutant forms of the chloroquine resistance transporter (PfCRT).
Clain, Jerome, Ecker, Andrea, Lehane, Adele, Fidock, David A   +3 more
core   +1 more source

Do health workers' preferences influence their practices? : Assessment of providers' attitude and personal use of new treatment recommendations for management of uncomplicated malaria, Tanzania [PDF]

, 2012
\ud \ud Due to growing antimalarial drug resistance, Tanzania changed malaria treatment policies twice within a decade. First in 2001 chloroquine (CQ) was replaced by sulfadoxine-pyrimethamine (SP) for management of uncomplicated malaria and by late 2006,
Lutambi Angelina M, Khatib, R. A., Rashid A Khatib, Masanja Irene M, Khatib Rashid A, Irene M Masanja, Masanja, Irene M, Lutambi, A. M., Angelina M Lutambi, Lutambi, Angelina M, Masanja, I. M., Khatib, Rashid A   +11 more
core   +2 more sources

Antimalarial qinghaosu/artemisinin: The therapy worthy of a Nobel Prize

Asian Pacific Journal of Tropical Biomedicine, 2016
Malaria is a major cause of human morbidity and mortality in the tropical endemic countries worldwide. This is largely due to the emergence and spread of resistance to most antimalarial drugs currently available.
Jerapan Krungkrai, Sudaratana Rochanakij Krungkrai   +1 more
doaj   +1 more source