Results 191 to 200 of about 54,267 (309)

Targeting Staphylococcus aureus Biofilms Through Aurisin Derivatives From Neonothopanus nambi of African Origin

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study describes the isolation and characterization of potent bioactive compounds from the fungal strain Neonothopanus nambi, followed by structural elucidation. The compounds shown are dimeric aristolane‐type sesquiterpenoids, identified as aurisins D (1) and B (2).
Syeda J. Khalid, Njogu M. Kimani, Yuanyuyue Huang, Mathias Müsken, Jan‐Peer Wennrich, Jonas Bentrup, Miroslav Kolařík, Josphat Clemet Matasyoh, Hedda Schrey   +8 more
wiley   +1 more source

Assessing the quality of antimalarial drugs in Equatorial Guinea: a follow-up study. [PDF]

BMJ Glob Health
Kaur H, Paris L, Mba Eyono JN, Nguema Avue RM, Phiri WP, Smith JM, Guerra CA, Riloha Rivas M, García GA.   +8 more
europepmc   +1 more source

Diversity-Oriented Synthesis-Facilitated Medicinal Chemistry: Toward the Development of Novel Antimalarial Agents

, 2014
Eamon Comer, Jennifer A. Beaudoin, Nobutaka Kato, Mark E. Fitzgerald, Richard W. Heidebrecht, Maurice duPont Lee, Daniela Masi, Marion Mercier, Carol A. Mulrooney, Giovanni Muncipinto, Ann Rowley, Keila N. Crespo-Lladó, Adelfa E. Serrano, Amanda K. Lukens, Roger C. Wiegand, Dyann F. Wirth, Michelle Palmer, Michael A. Foley, Benito Muñoz, Christina Scherer, Jeremy R. Duvall, Stuart L. Schreiber   +21 more
openalex   +2 more sources

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza, Alina Sadaf, Reeha Mushtaq, Mirza Abid Mehmood, Luqman Amrao, Fakhar Islam, Muhammad Afzaal, Mohd Asif Shah   +7 more
wiley   +1 more source

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George, Lobna A. Elsadek, Max Deering, Larissa Costa de Almeida, Jasper L. Tyler, Adam Noble, Valerie J. Paul, Hendrik Luesch, Craig P. Butts, Varinder K. Aggarwal   +9 more
wiley   +2 more sources

A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum. [PDF]

Angew Chem Int Ed Engl
Bravo P, Diamanti E, Hamed MM, Bizzarri L, Wiedemar N, Passecker A, Brancucci NMB, Albisetti A, Gumpp C, Illarionov B, Fischer M, Witschel M, Schehl T, Hahne H, Mäser P, Rottmann M, Hirsch AKH.   +16 more
europepmc   +1 more source

Additional file 1 of Access to antimalarial drugs in the Asia–Pacific region during health emergency: a multinational cross-sectional investigation between 2020 and 2022

Sun, Yinuo, Cui, Yuxuan, Huang, Yangmu, Xu, Ming   +3 more
openalex   +1 more source

Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers

, 2013
Richard K. Amewu, James Chadwick, Afthab Hussain, Somnath Panda, Rinki Rinki, Omar Janneh, Stephen A. Ward, Candel Miguel, Hollie Burrell‐Saward, Livia Vivas, Paul M. O’Neill   +10 more
openalex   +2 more sources

Pharmacokinetics of the Antimalarial Drug Piperaquine in Healthy Vietnamese Subjects [PDF]

, 2008
Nguyen Trong Chinh, Nguyen Ngoc Quang, Nguyễn Xuân Thành, Bui Dai, Thomas Travers, Michael D. Edstein   +5 more
openalex   +1 more source

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source