Results 191 to 200 of about 90,085 (338)

The use of antimalarial drugs.

open access: yesSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974
A general review is given of the antimalarial drugs currently available and in common use, with special reference to those found to be of most benefit in Southern Africa.S. Afr. Med. J., 48, 1314 (1974)
openaire   +3 more sources

GNS561 (ezurpimtrostat), a small basic lipophilic molecule, prevents lupus phenotype in a pristane‐induced lupus mouse model

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 16, Page 3786-3799, August 2025.
Background and Purpose Systemic lupus erythematosus is an autoimmune, multisystemic disease affecting all organs in the body. Accrued evidence has elucidated a role for autophagy in the onset and severity of systemic lupus erythematosus. The antimalarial drug hydroxychloroquine constitutes the cornerstone of standard of care for systemic lupus ...
Eya Toumi   +10 more
wiley   +1 more source

THE SYNTHESIS OF POTENTIAL ANTIMALARIALS

open access: hybrid, 1946
James F. Mead   +4 more
openalex   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou   +4 more
wiley   +1 more source

THE SYNTHESIS OF POTENTIAL ANTIMALARIALS

open access: hybrid, 1947
ALLEN E. SENEAR   +2 more
openalex   +1 more source

Repurposing of FDA‐Approved Drugs to Disrupt Iron Uptake in Mycobacterium abscessus: Targeting Salicylate Synthase as a Novel Approach

open access: yesChemical Biology &Drug Design, Volume 106, Issue 2, August 2025.
A drug repurposing strategy was applied against M. abscessus, through a virtual screening of FDA approved drugs on salicylate synthase. Eleven potential ligands were found; among these, three were confirmed as potent inhibitors of the enzyme. ABSTRACT Non‐tuberculous mycobacteria (NTM) are opportunistic pathogens that lead to severe, persistent ...
Giovanni Stelitano   +7 more
wiley   +1 more source

The Diagnostic Performance of a Sysmex XN‐31 Automated Malaria Analyzer vs. Expert Microscopy

open access: yesInternational Journal of Laboratory Hematology, Volume 47, Issue 4, Page 613-621, August 2025.
ABSTRACT Introduction Malaria is a common and life‐threatening infection. Malaria diagnosis needs to be fast and reliable. Although malaria microscopy is currently the gold standard, it is laborious, requires extensive training, and relies heavily on the proficiency of microscopists.
S. Onsongo   +9 more
wiley   +1 more source

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