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Abstract: A growing body of data from clinical and preclinical studies suggests that the glutamatergic system may represent a novel therapeutic target for severe recurrent mood disorders. Since synapse‐specific glutamate receptor expression/localization is known to play critical roles in synaptic plasticity, we investigated the effects of mood ...
Cynthia Falke+5 more
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This retrospective study was conducted to evaluate the relationship between the mood-stabilizing agents lithium, carbamazepine, and divalproex sodium and time course of drug response as measured by length of hospital stay.Seventy-eight patients were evaluated.
M A, Frye+4 more
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Stimulants, antidepressants, antimanics, anticonvulsants, and psychotomimetic agents
Bev-Lorraine True, Robert H. Dreisbach
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Antimanic agents : a pharmacoepidemiologic study
Neurologia Croatica. Supplement, 1997In the treatment of bipolar affective disorders many agents have been used. An epidemiologic descriptive analysis of the drug treatment in patients with bipolar affective disorders often includes lithium, carbamazepine or valproate. These agents have shown to be effective in the acute or maintenance treatment of mania in numerous clinical trials and ...
Makarić, Gordan+3 more
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Health-economic implications of the onset of action of antimanic agents.
The Journal of clinical psychiatry, 1997Three medications, lithium, valproate, and carbamazepine, have been shown to be effective in the treatment of acute mania in randomized, controlled clinical trials. Additional research over the past decade has provided data regarding potential differences between these medications according to their time course of onset and clinical predictors of ...
P E, Keck, S L, McElroy, J A, Bennett
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