Results 31 to 40 of about 3,197,416 (181)

Drugs that lower the seizure threshold [PDF]

open access: yes, 2016
Drugs with potential to lower the seizure threshold are numerous and diverse. Whether they contribute to clinically overt seizures depends on the dosage in which they are taken, the time-course of their effects and the susceptibility of the patient ...
Alper   +48 more
core   +1 more source

Optical Drug Monitoring: Photoacoustic Imaging of Nanosensors to Monitor Therapeutic Lithium in Vivo [PDF]

open access: yes, 2015
Personalized medicine could revolutionize how primary care physicians treat chronic disease and how researchers study fundamental biological questions. To realize this goal, we need to develop more robust, modular tools and imaging approaches for in vivo
Bakker E.   +46 more
core   +1 more source

Antidepressant use and risk of suicide and attempted suicide or self harm in people aged 20 to 64: cohort study using a primary care database [PDF]

open access: yes, 2015
Objective To assess the associations between different antidepressant treatments and the rates of suicide and attempted suicide or self harm in people with depression. Design Cohort study.
Arthur, Antony   +5 more
core   +2 more sources

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

open access: yesActa Psychiatrica Scandinavica, Volume 152, Issue 3, Page 156-179, September 2025.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos   +2 more
wiley   +1 more source

Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]

open access: yes, 2002
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B.   +3 more
core   +1 more source

Defining Treatment‐Resistant Bipolar Depression: Recommendations From the ISBD Task Force

open access: yesBipolar Disorders, Volume 27, Issue 6, Page 411-423, September 2025.
ABSTRACT Objective Despite the availability of approved treatments, a substantial proportion of patients with bipolar disorder experience treatment‐resistant bipolar depression (TRBD), characterized by persistent depressive symptoms unresponsive to standard therapies. However, a universally accepted definition of TRBD is lacking.
Eduard Vieta   +29 more
wiley   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

open access: yes, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Treatment Implications of Predominant Polarity and the Polarity Index: A Comprehensive Review

open access: yesInternational Journal of Neuropsychopharmacology, 2015
Background: Bipolar disorder (BD) is a serious and recurring condition that affects approximately 2.4% of the global population. About half of BD sufferers have an illness course characterized by either a manic or a depressive predominance.
A. Carvalho   +7 more
semanticscholar   +1 more source

The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review

open access: yesInternational Journal of Mental Health Nursing, Volume 34, Issue 4, July 2025.
ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley   +1 more source

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

open access: yes, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core  

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