EFFECTS OF METHOTREXATE ON PROLIFERATION OF HUMAN KERATINOCYTES IN VITRO [PDF]
, 1977 Normal human keratinocytes, propagated as epithelial outgrowths in vitro, were exposed to different concentrations of methotrexate (MTX) for different periods of time. After a 1-hr exposure, DNA synthesis was inhibited in a reversible manner.
Chiarello, Stephen +3 more
core +1 more source
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations [PDF]
, 2009 The dose-delivery schedule of conventional chemotherapy, which determines its efficacy and toxicity, is based on the maximum tolerated dose. This strategy has lead to cure and disease control in a significant number of patients but is associated with ...
A Ottaiano +53 more
core +4 more sources
Therapeutic efficacy study of novel 5-FU-loaded PMM 2.1.2-based microspheres on C6 glioma [PDF]
, 2003 The aim of this study was to evaluate the potential of poly(methylidene malonate 2.1.2) as a new drug delivery system to the central nervous system.
A. Vonarbourg +7 more
core +2 more sources
Chemotherapy and skin reactions. [PDF]
, 2012 BACKGROUND:New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a ...
Bianca D +6 more
core +1 more source
Pharmacovigilance in cancer chemotherapy in regional cancer center of Eastern India: prospective observational study [PDF]
, 2017 Background: Globally cancer is the leading cause of morbidity and mortality with annual death rate of 12%. According Indian Council of Medical Research, more than 1300 Indians die every day due to cancer.
Mishra, Vedvyas +4 more
core +2 more sources
Macromolecular platinum-based anticancer agents [PDF]
, 2013 A thesis submitted to the faculty of Science, University of the Witwatersrand, in fulfillment of the degree of Doctor of Philosophy in Science Johannesburg, 2012Platinum is nowadays one of the best and widely used antitumor agents in cancer chemotherapy.
Diainabo, Kayembe Jacques
core
26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines [PDF]
, 2013 It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is commonly used as internal ...
Abdul-Hadi, Soraya +7 more
core +4 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Antioxidant supplementation in cancer: Potential interactions with conventional chemotherapy and radiation therapy [PDF]
, 2001 Several issues are addressed in this discussion of the advantages and disadvantages of supplemental anti-oxidants during cancer treatment with chemotherapy and/or radiation ...
Staff, Clinic
core +1 more source
Macromolecular Materials and Engineering, EarlyView.The poloxamer Pluronic‐F‐127‐based hydrogels are improved by the implementation of polysaccharides with different concentration ranges and structural organizations. The interactions between the polysaccharide structures and the poloxamer micellar aggregation confer the system better rheological properties and longer drug release times explained by ...
Marcos Blanco‐López +4 more
wiley +1 more source