Results 11 to 20 of about 7,490 (132)

Childbearing in women diagnosed with cancer during reproductive age. [PDF]

Acta Obstet Gynecol Scand
Compared to cancer‐free women, the probability of childbearing within 5 years of a cancer diagnosis was reduced, particularly among those diagnosed over the age of 30. Age at diagnosis and antineoplastic treatment were key factors, with treatment also increasing the use of assisted reproduction. Abstract Introduction Fertility after cancer represents a
Esposito G, Cantarutti A, Franchi M, Peccatori FA, Scarfone G, Negri E, Corrao G, Parazzini F, La Vecchia C.   +8 more
europepmc   +2 more sources

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review. [PDF]

J Appl Toxicol
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Pinto TG, da Silva Avanci L, de Aguiar GC, de Souza DV, Cury PR, Renno ACM, Ribeiro DA.   +6 more
europepmc   +2 more sources

26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines [PDF]

, 2013
It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is commonly used as internal ...
Abdul-Hadi, Soraya, Bermúdez, María José, Maestro, Miguel, Martínez Ordóñez, Anxo, Mouriño, Antonio, Pérez-Fernández, Román, Sendón Lago, Juan José, Seoane, Samuel   +7 more
core   +4 more sources

Novel Approaches for Concurrent Irradiation in Locally Advanced Cervical Cancer: Platinum Combinations, Non-Platinum-Containing Regimens, and Molecular Targeted Agents

Obstetrics and Gynecology International, 2013
Despite the available prevention and early detection strategies, squamous-cell carcinoma of the uterine cervix is still diagnosed as locally advanced disease in a considerable proportion of patients.
Giannis Mountzios, Aspasia Soultati, Dimitrios Pectasides, Meletios A. Dimopoulos, Christos A. Papadimitriou   +4 more
doaj   +1 more source

A simple and robust method for connecting small-molecule drugs using gene-expression signatures [PDF]

, 2008
Interaction of a drug or chemical with a biological system can result in a gene-expression profile or signature characteristic of the event. Using a suitably robust algorithm these signatures can potentially be used to connect molecules with similar ...
B Efron, CC Ting, J Frasor, J Lamb, JD Storey, JJ Chen, JS Warrington, KB Glaser, L Tian, M Lee, N Fujimoto, N Sathyamoorthy, PA Horwitz, R Januchowski, S McHugh, SD Zhang, Shu-Dong Zhang, ST Matalon, Timothy W Gant, VW Armstrong, Y Chen   +20 more
core   +5 more sources

Multi-Institutional experience with FOLFIRINOX in pancreatic adenocarcinoma [PDF]

, 2012
Combination chemotherapy with FOLFIRINOX (oxaliplatin, irinotecan, fluorouracil, and leucovorin) was shown to be effective in a large phase III trial.
Gao, Feng, Linehan, David, Lockhart, A Craig, Lubner, Sam, McWilliams, Robert, Menias, Christine, Peddi, Parvin F, Picus, Joel, Sorscher, Steven M, Suresh, Rama, Tan, Benjamin R, Wang, Jian, Wang-Gilliam, Andrea   +12 more
core   +3 more sources

Chemotherapy and skin reactions. [PDF]

, 2012
BACKGROUND:New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a ...
Bianca D, Cameli N, FABBROCINI, GABRIELLA, MARIANO, MARIA, MONFRECOLA, GIUSEPPE, PANARIELLO, LUIGIA, Romano MC   +6 more
core   +1 more source

Assay of some biologically active antimetabolite antineoplastic drugs with N-bromosuccinimide reagent

, 2005
Department of Chemistry, University of Allahabad, Allahabad-211 002, India E-mail: poonamjai92@rediffmail.com Poonam_J9672000@yahoo.com Manuscript received 8 October 2004, revised 10 August 2005. accepted 17 August 2005 In the present investigation a simple, sensitive, selective, quick and convenient method has been developed for the determination of ...
Jaiswal, Poonam, P. K. Dwivedi, I. C. Shukla   +2 more
openaire   +1 more source

Therapeutic efficacy study of novel 5-FU-loaded PMM 2.1.2-based microspheres on C6 glioma [PDF]

, 2003
The aim of this study was to evaluate the potential of poly(methylidene malonate 2.1.2) as a new drug delivery system to the central nervous system.
A. Vonarbourg, C. Passirani-Malleret, E. Fournier, J.P. Benoît, L. Lemaire, N. Colin, P. Menei, S. Sagodira   +7 more
core   +4 more sources

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H., Ballestrero A., Bellamy W. T., Betanzos-Lara S., Bozic I., Bushra Qamar, Carew J. S., Castonguay A., Chan J., Constantini P., Dai Y., Degterev A., Dindo D., Doroshow J. H., Dyke M. W. Van, Fagan V., Finnilä S., Frank J. E., Fu Y., Fu Y., Gaiddon C., Garbutcheon-Singh K. B., Hannon M. J., Hartinger C. G., Hileman E. A., Holbeck S., Huo H., Ian Hands-Portman, Isolda Romero-Canelón, Jessica M. Hearn, Jordan M. A., Jungwirth U., Kelland L., Kerr J. F., Kroemer G., Lazebnik Y. A., Liu Z., Liu Z., Liu Z., Lu J.-J., McKeage M. J., Millar A. W., Monneret C., Nagata S., Park G. Y., Paull K., Perchellet E. M., Peter J. Sadler, Petrelli A., Pittella F., Porteous C. M., Pracharova J., Purewal M., Rai S. S., Rixe O., Saraste A., Shoemaker R. H., Shoemaker R. H., Siddik Z., Sidler D., Tsutsui T., Türk D., Van den Bogert C., Zalacaín M., Zhang Y.-W., Zhe Liu, Zhou D.-F., Zhu Z.   +67 more
core   +1 more source