Results 21 to 30 of about 6,952 (109)

Asthma Alleviation by Ginsenoside Rb1 via Promotion of Treg Proliferation and Inflammatory T Cell Inhibition

open access: yesAllergy, EarlyView.
Screening of 250 natural products identified ginsenoside Rb1 (gRb1) as a potent modulator of regulatory T cells (Tregs) and inflammatory T cells. gRb1 increased IL‐10‐ and TGF‐β‐expressing Tregs while reducing Th17, Th1, and Th2 populations in both asthma model mice and human PBMCs.
Susanna Choi   +14 more
wiley   +1 more source

Analysis of anticancer drugs using thin layer chromatography- A review [PDF]

open access: yes, 2018
WOS: 000445922100001Cancer is a fatal disease and cancer incidence is increasing from day to day. Thus, anticancer drugs are widely used and their analysis requires simple and effective analytical procedures.
Uğur, Alper, Yeniceli Uğur, Duygu
core   +1 more source

Chemotherapy‐Induced Neuropathy Affecting the Gastrointestinal Tract

open access: yesNeurogastroenterology &Motility, EarlyView.
Chemotherapy (with/without immunotherapy/radiotherapy) may induce neurotoxic effects on the gastrointestinal innervation. Chemotherapy‐induced enteric neuropathy (CIEN) and, probably, neurotoxicity affecting the extrinsic innervation of the gut and the brain underlie the frequent and impactful gut dysfunctions and brain–gut axis (BGA) disorders ...
Gema Vera, Kulmira Nurgali, Raquel Abalo
wiley   +1 more source

Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Anticancer chemotherapy is an underappreciated contributor to cancer cachexia, an often‐irreversible body‐wasting condition that causes 20%–30% of cancer‐related deaths. An obstacle to predicting, monitoring and understanding the mechanisms underlying chemotherapy cachexia is that each cancer (and subtype) is assigned different ...
Dean G. Campelj   +9 more
wiley   +1 more source

Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]

open access: yes, 1986
The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R.   +5 more
core   +1 more source

Adjuvant Chemotherapy May be Waived for Breast Cancer Nonresponders to Neoadjuvant Chemotherapy: A Population‐Based Large Cohort Study

open access: yesThoracic Cancer, Volume 16, Issue 9, May 2025.
Adjuvant chemotherapy (AC) showed limited benefit in breast cancer patients who did not respond to neoadjuvant chemotherapy (NAC). Overall survival was similar between those who received AC and those who did not. Multivariate and subgroup analyses confirmed no clear advantage of AC.
Lixi Li   +5 more
wiley   +1 more source

Prognostic and predictive implications of sterile alpha motif and HD domain‐containing protein 1 (SAMHD1) expression in breast cancer

open access: yesInternational Journal of Cancer, Volume 156, Issue 8, Page 1621-1633, 15 April 2025.
What's new? Sterile alpha motif and HD domain‐containing protein 1 (SAMHD1), a dNTP hydrolase, acts as tumor suppressor in cancer, but its role in breast cancer is not well‐studied. Here, the authors analyzed gene and protein expression in a cohort of patients with early breast cancer.
Maria Kouvaraki   +17 more
wiley   +1 more source

Enzymatic Upgrading of Biomass‐Derived Aldoses to Rare Deoxy Ketoses Catalyzed by Transketolase Variants

open access: yesChemSusChem, Volume 18, Issue 8, April 14, 2025.
A sustainable, convenient, scalable, one‐step method for the two‐carbon chain elongation of cheap, biomass‐derived pentoses (l‐arabinose, and 2‐deoxy‐d‐ribose) and a hexose (l‐rhamnose) was developed to produce Cn+2 deoxy ketoses (C‐7 and C‐8) using transketolase, an enzyme catalyzing the irreversible transfer of a ketol group from an α‐ketoacid to an ...
Giuseppe Arbia   +6 more
wiley   +1 more source

Systemic 5-fluorouracil induced lupus erythematosus: a review of the literature [PDF]

open access: yes, 2019
Drug-induced subacute cutaneous lupus erythematosus (SCLE) is the most common subtype of drug-induced systemic lupus erythematosus and has been associated with more than 100 drugs.
Marsch, Amanda F, Shakhbazova, Anastasia
core  

Injectable 2D‐MoS2‐integrated Bioadhesive Hydrogel as Photothermal‐Derived and Drug‐Delivery Implant for Colorectal Cancer Therapy

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
An injectable, adhesive hydrogel integrating 2D‐MoS2 and 5‐fluorouracil (AlgNB/MoS2/5‐FU) is developed for near‐infrared‐triggered photothermal therapy and localized drug delivery. The adhesive hydrogel demonstrates superior tumor anchoring, efficient photothermal conversion, and synergistic inhibition of colorectal cancer progression, offering a ...
Xiaojun Long   +8 more
wiley   +1 more source

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